Na-doped hydroxyapatite coating on carbon/carbon composites: Preparation, in vitro bioactivity and biocompatibility

被引：59

作者：

Li, Hejun ^{[1
]}

Zhao, Xueni ^{[1
]}

Cao, Sheng ^{[1
]}

Li, Kezhi ^{[1
]}

Chen, Mengdi ^{[1
]}

Xu, Zhanwei ^{[1
]}

Lu, Jinhua ^{[1
]}

Zhang, Leilei ^{[1
]}

机构：

[1] Northwestern Polytech Univ, State Key Lab Solidificat Proc, Xian 710072, Shaanxi, Peoples R China

来源：

APPLIED SURFACE SCIENCE | 2012年 / 263卷

基金：

中国国家自然科学基金; 中国博士后科学基金;

关键词：

Hydroxyapatite; Coating; Electrochemical deposition; Carbon/carbon composites; Simulated body fluid; CALCIUM-PHOSPHATE COATINGS; ELECTROCHEMICAL DEPOSITION; APATITE FORMATION; TITANIUM; HA; ELECTRODEPOSITION; MINERALIZATION; DISSOLUTION; FABRICATION; INDUCTION;

D O I：

10.1016/j.apsusc.2012.09.022

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Na-doped hydroxyapatite (Na-HA) coating was directly prepared onto carbon/carbon (C/C) composites using electrochemical deposition (ECD) and themeanthickness of the coating is approximately 10 +/- 2 mu m. The formed Na-HA crystals which are Ca-deficient, are rod-like with a hexagonal cross section. The Na/P molar ratios of the coating formed on C/C substrate is 0.097. During the deposition, the Na-HA crystals grow in both radial and longitudinal directions, and faster along the longitudinal direction. The pattern formation of crystal growth leads to dense coating which would help to increase the bonding strength of the coating. The average shear bonding strength of Na-HA coating on C/C is 5.55 +/- 0.77 MPa. The in vitro bioactivity of the Na-HA coated C/C composites were investigated by soaking the samples in a simulated body fluid (SBF) for 14 days. The results indicate that the Na-HA coated C/C composites can rapidly induce bone-like apatite nucleation and growth on its surface in SBF. The in vitro cellular biocompatibility tests reveal that the Na-HA coating was better to improve the in vitro biocompatibility of C/C composites compared with hydroxyapatite (HA) coating. It was suggested that the Na-HA coating might be an effective method to improve the surface bioactivity and biocompatibility of C/C composites. (C) 2012 Elsevier B. V. All rights reserved.

引用

页码：163 / 173

页数：11

共 47 条

[1] HIGH-RESOLUTION ELECTRON-MICROSCOPY OF HYDROXYAPATITE GROWN IN DILUTE-SOLUTIONS [J].