Inflammatory Pseudotumor of Urinary Bladder: A Masquerader of Bladder Malignancy

Inflammatory pseudotumor of urinary bladder is a rare benign disease of unknown etiology, characterized by nonneoplastic proliferation of fibroblastic spindle cells, in a background of myxoid and granulation tissue. We report a case of an inflammatory pseudotumor of urinary bladder and discuss the important differentials. A 47-year-old woman presented with longstanding frequency and urgency of micturition. Ultrasound pelvis, color Doppler, computed tomography, and magnetic resonance imaging were performed. Focal bladder wall thickening at the dome was observed. In addition, there was a heterogeneous solid cystic intramural lesion within this bladder wall thickening showing peripheral rim enhancement with nonenhancing central component. Repeated urine cultures were sterile and urine cytology was found to be negative for malignancy. Finally, histopathology and immunohistochemistry confirmed this lesion to be inflammatory pseudotumor.