Successful treatment of acute symptomatic extensive portal venous system thrombosis by 7-day systemic thrombolysis

被引：3

作者：

Gao, Fang-Bo ^{[1
,2
]}

Wang, Le ^{[1
]}

Zhang, Wen-Xiu ^{[1
]}

Shao, Xiao-Dong ^{[1
]}

Guo, Xiao-Zhong ^{[1
]}

Qi, Xing-Shun ^{[1
]}

机构：

[1] Gen Hosp Northern Theater Command, Dept Gastroenterol, 83 Wenhua Rd, Shenyang 110840, Liaoning, Peoples R China

[2] Postgrad Coll, Shenyang Pharmaceut Univ, Shenyang 110016, Liaoning, Peoples R China

来源：

WORLD JOURNAL OF GASTROINTESTINAL SURGERY | 2022年 / 14卷 / 09期

关键词：

Portal vein; Mesenteric vein; Thrombosis; Thrombolysis; Anticoagulation; Deep vein thrombosis; VEIN-THROMBOSIS;

D O I：

10.4240/wjgs.v14.i9.1082

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Acute portal venous system thrombosis (PVST) can cause acute mesenteric ischemia and even intestinal infarction, which are potentially fatal, and requires recanalization in a timely fashion. Herein, we report a 56-year-old man with acute non-cirrhotic symptomatic extensive PVST who achieved portal vein recanalization after systemic thrombolysis combined with anticoagulation. Initially, anticoagulation with enoxaparin sodium for 4 d was ineffective, and then systemic thrombolysis for 7 d was added. After that, his abdominal pain completely disappeared, and portal vein system vessels became gradually patent. Long-term anticoagulation therapy was maintained. In conclusion, 7-d systemic thrombolysis may be an effective and safe choice of treatment for acute symptomatic extensive PVST which does not respond to anticoagulation therapy.

引用

页码：1082 / 1085

页数：4

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