Previous Lung Diseases and Lung Cancer Risk: A Pooled Analysis From the International Lung Cancer Consortium

被引：152

作者：

Brenner, Darren R. ^{[1
,2
]}

Boffetta, Paolo ^{[3
,4
]}

Duell, Eric J. ^{[5
]}

Bickeboeller, Heike ^{[6
]}

Rosenberger, Albert ^{[6
]}

McCormack, Valerie ^{[7
]}

Muscat, Joshua E. ^{[8
]}

Yang, Ping ^{[11
]}

Wichmann, H. -Erich ^{[12
]}

Brueske-Hohlfeld, Irene ^{[12
]}

Schwartz, Ann G. ^{[13
,14
]}

Cote, Michele L. ^{[13
,14
]}

Tjonneland, Anne ^{[15
]}

Friis, Soren ^{[15
]}

Le Marchand, Loic ^{[16
]}

Zhang, Zuo-Feng ^{[17
]}

Morgenstern, Hal ^{[18
,19
,20
]}

Szeszenia-Dabrowska, Neonila ^{[21
]}

Lissowska, Jolanta ^{[22
,23
]}

Zaridze, David ^{[24
]}

Rudnai, Peter ^{[25
]}

Fabianova, Eleonora ^{[26
]}

Foretova, Lenka ^{[27
]}

Janout, Vladimir ^{[28
]}

Bencko, Vladimir ^{[29
]}

Schejbalova, Miriam ^{[29
]}

Brennan, Paul ^{[7
]}

Mates, Ioan N. ^{[30
]}

Lazarus, Philip ^{[9
,10
]}

Field, John K. ^{[31
]}

Raji, Olaide ^{[31
]}

McLaughlin, John R. ^{[1
,2
]}

Liu, Geoffrey ^{[32
]}

Wiencke, John ^{[33
]}

Neri, Monica ^{[34
]}

Ugolini, Donatella ^{[35
,36
,37
,38
,39
]}

Andrew, Angeline S. ^{[40
]}

Lan, Qing ^{[41
]}

Hu, Wei ^{[41
]}

Orlow, Irene ^{[42
]}

Park, Bernard J. ^{[43
]}

Hung, Rayjean J. ^{[1
,2
]}

机构：

[1] Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Toronto, ON M5T 3L9, Canada

[2] Univ Toronto, Div Epidemiol, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada

[3] Mt Sinai Sch Med, Inst Translat Epidemiol, New York, NY USA

[4] Int Prevent Res Inst, Lyon, France

[5] Catalan Inst Oncol, Unit Nutr Environm & Canc, Canc Epidemiol Res Program, Barcelona, Spain

[6] Univ Gottingen, Sch Med, Dept Genet Epidemiol, Gottingen, Germany

[7] Int Agcy Res Canc, F-69372 Lyon, France

[8] Penn State Univ, Penn State Canc Inst, Div Epidemiol, State Coll, PA USA

[9] Penn State Univ, Penn State Canc Inst, Dept Pharmacol, State Coll, PA USA

[10] Penn State Univ, Penn State Canc Inst, Dept Hlth Evaluat Sci, State Coll, PA USA

[11] Mayo Clin, Epidemiol & Genet Lung Canc Res Program, Rochester, MN USA

[12] German Res Ctr Environm Hlth, Helmholtz Ctr Munich, Inst Epidemiol, Neuherberg, Germany

[13] Wayne State Univ, Sch Med, Dept Oncol, Detroit, MI USA

[14] Karmanos Canc Inst, Detroit, MI USA

[15] Danish Canc Soc, Inst Canc Epidemiol, Copenhagen, Denmark

[16] Univ Hawaii, Ctr Canc, Honolulu, HI 96822 USA

[17] Univ Calif Los Angeles, Sch Publ Hlth, Dept Epidemiol, Los Angeles, CA 90024 USA

[18] Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA

[19] Univ Michigan, Sch Publ Hlth, Dept Environm Hlth Sci, Ann Arbor, MI 48109 USA

[20] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA

[21] Inst Occupat Med, Dept Epidemiol, Lodz, Poland

[22] M Sklodowska Curie Mem Canc Ctr, Dept Canc Epidemiol & Prevent, Warsaw, Poland

[23] Inst Oncol, Warsaw, Poland

[24] Russian Acad Med Sci, Canc Res Ctr, Inst Carcinogenesis, Moscow, Russia

[25] Natl Inst Environm Hlth, Fodor Jozsef Natl Ctr Publ Hlth, Budapest, Hungary

[26] Specialized State Hlth Inst, Dept Occupat Hlth, Banska Bystrica, Slovakia

[27] Masaryk Mem Canc Inst, Dept Canc Epidemiol & Genet, Brno, Czech Republic

[28] Palacky Univ, Dept Prevent Med, Fac Med, CR-77147 Olomouc, Czech Republic

[29] Charles Univ Prague, Fac Med 1, Inst Hyg & Epidemiol, Prague, Czech Republic

[30] Univ Med & Pharm Carol Davila, Bucharest, Romania

[31] Univ Liverpool, Canc Res Ctr, Roy Castle Lung Canc Res Programme, Dept Mol & Clin Canc Med, Liverpool L69 3BX, Merseyside, England

[32] Princess Margaret Hosp, Ontario Canc Inst, Toronto, ON M4X 1K9, Canada

[33] Univ Calif San Francisco, Sch Med, Dept Epidemiol & Biostat, San Francisco, CA USA

[34] IRCCS Ist Ricovero & Cura Carattere Sci San Raffa, Unit Clin & Mol Epidemiol, Rome, Italy

[35] Univ Genoa, Epidemiol Unit, Genoa, Italy

[36] Univ Genoa, Biostat Unit, Genoa, Italy

[37] Natl Inst Canc Res, Epidemiol Unit, Genoa, Italy

[38] Natl Inst Canc Res, Biostat Unit, Genoa, Italy

[39] Natl Inst Canc Res, Unit Clin Trials, Genoa, Italy

[40] Dartmouth Med Sch, Norris Cotton Canc Ctr, Unit Biostat & Epidemiol, Dept Community & Family Med, Lebanon, NH USA

[41] NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA

[42] Mem Sloan Kettering Canc Ctr, Dept Epidemiol & Biostat, New York, NY 10021 USA

[43] Mem Sloan Kettering Canc Ctr, Dept Surg, New York, NY 10021 USA

来源：

AMERICAN JOURNAL OF EPIDEMIOLOGY | 2012年 / 176卷 / 07期

基金：

加拿大健康研究院; 美国国家卫生研究院;

关键词：

bronchitis; chronic; emphysema; lung diseases; lung neoplasms; meta-analysis; pneumonia; pulmonary disease; chronic obstructive; tuberculosis; OBSTRUCTIVE PULMONARY-DISEASE; RESIDENTIAL RADON; PREDICTION MODEL; NEVER-SMOKERS; INFLAMMATION; SMOKING; EPIDEMIOLOGY; ASSOCIATION; VALIDATION; EXPOSURE;

D O I：

10.1093/aje/kws151

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

To clarify the role of previous lung diseases (chronic bronchitis, emphysema, pneumonia, and tuberculosis) in the development of lung cancer, the authors conducted a pooled analysis of studies in the International Lung Cancer Consortium. Seventeen studies including 24,607 cases and 81,829 controls (noncases), mainly conducted in Europe and North America, were included (19842011). Using self-reported data on previous diagnoses of lung diseases, the authors derived study-specific effect estimates by means of logistic regression models or Cox proportional hazards models adjusted for age, sex, and cumulative tobacco smoking. Estimates were pooled using random-effects models. Analyses stratified by smoking status and histology were also conducted. A history of emphysema conferred a 2.44-fold increased risk of lung cancer (95 confidence interval (CI): 1.64, 3.62 (16 studies)). A history of chronic bronchitis conferred a relative risk of 1.47 (95 CI: 1.29, 1.68 (13 studies)). Tuberculosis (relative risk 1.48, 95 CI: 1.17, 1.87 (16 studies)) and pneumonia (relative risk 1.57, 95 CI: 1.22, 2.01 (12 studies)) were also associated with lung cancer risk. Among never smokers, elevated risks were observed for emphysema, pneumonia, and tuberculosis. These results suggest that previous lung diseases influence lung cancer risk independently of tobacco use and that these diseases are important for assessing individual risk.

引用

页码：573 / 585

页数：13

共 70 条

[1]

[Anonymous], TRENDS COPD CHRON BR

[2]

[Anonymous], 2007, CANCER EPIDEM BIOMAR, DOI DOI 10.1158/1055-9965.EPI-06-0823

[3]

[Anonymous], CAN CANC STAT 2010

[4]

[Anonymous], TRENDS TUB MORB MORT

[5] Inflammation and lung cancer: Roles of reactive oxygen/nitrogen species [J].

Azad, Neelam ;

Rojanasakul, Yon ;

Vallyathan, Val .

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS, 2008, 11 (01) :1-15

[6] UK Lung Screen (UKLS) nodule management protocol: modelling of a single screen randomised controlled trial of low-dose CT screening for lung cancer [J].

Baldwin, D. R. ;

Duffy, S. W. ;

Wald, N. J. ;

Page, R. ;

Hansell, D. M. ;

Field, J. K. .

THORAX, 2011, 66 (04) :308-313

[7]

Ballaz Santiago, 2003, Clin Lung Cancer, V5, P46, DOI 10.3816/CLC.2003.n.021

[8] Validation of self-reported chronic obstructive pulmonary disease in a cohort study of nurses [J].

Barr, RG ;

Herbstman, J ;

Speizer, FE ;

Camargo, CA .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 2002, 155 (10) :965-971

[9] High cumulative risk of lung cancer death among smokers and nonsmokers in Central and Eastern Europe [J].

Brennan, Paul ;

Crispo, Anna ;

Zaridze, David ;

Szeszenia-Dabrowska, Neonila ;

Rudnai, Peter ;

Lissowska, Jolanta ;

Fabianova, Eleonora ;

Mates, Dana ;

Bencko, Vladimir ;

Foretova, Lenka ;

Janout, Vladimir ;

Fletcher, Tony ;

Boffetta, Paolo .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 2006, 164 (12) :1233-1241

[10] Previous Lung Diseases and Lung Cancer Risk: A Systematic Review and Meta-Analysis [J].

Brenner, Darren R. ;

McLaughlin, John R. ;

Hung, Rayjean J. .

PLOS ONE, 2011, 6 (03)

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