Synthesis of a new class of chiral β-mercaptoalcohols from amino acids

被引:0
|
作者
Ge, JF [1 ]
Shen, ZX [1 ]
Zhang, LF [1 ]
Zhang, YW [1 ]
机构
[1] Suzhou Univ, Dept Chem & Chem Engn, Suzhou 215006, Jiangsu, Peoples R China
关键词
beta-mercaptoalcohols; amino acids; synthesis;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The syntheses of three new optically active beta -mercaptoalcohols, (R)-1,1-diphenyl-2-mercapto-3-methyl-1-butanol, (R)-1,1-diphenyl-2-mercapto-4-methyl-1-pentanol, and (R)-1,1-diphen-2-mercapto-1-benzenepropanol from the corresponding amino adds am described. The enantiomeric excesses of these beta -mercaptoalcohols were determined by H-1 NMR as their (S)-mandeloyl derivatives.
引用
收藏
页码:79 / 84
页数:6
相关论文
共 50 条
  • [41] New Chiral Calixarene Derivatives: Syntheses and Their Chiral Recognition Toward Amino Acids by UV-Vis Spectroscopy
    GU Jin-ying1
    2. Department of Chemistry
    ChemicalResearchinChineseUniversities, 2008, (01) : 106 - 109
  • [42] Diastereoselective synthesis of α-methylpyroglutamates from α,β-didehydro α-amino acids
    Alvarez-Ibarra, C
    Csáky, AG
    de la Oliva, CG
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2002, 2002 (24) : 4190 - 4194
  • [43] Asymmetric synthesis of isoquinoline derivatives from amino acids
    Sieck, O
    Ehwald, M
    Liebscher, J
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2005, 2005 (04) : 663 - 672
  • [44] New chiral calixarene derivatives: Syntheses and their chiral recognition toward amino acids by UV-Vis spectroscopy
    Gu Jin-ying
    He Wan-ping
    Shi Xian-fa
    Ji Liang-nian
    CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2008, 24 (01) : 106 - 109
  • [45] Straightforward synthesis of a novel class of rigid bicyclic dipeptidomimetics from simple dipeptides: Fused imidazole amino acids
    Haberhauer, G
    Rominger, F
    SYNLETT, 2003, (06) : 780 - 784
  • [46] A versatile synthetic route to chiral quinoxaline derivatives from amino acids precursors
    El-Faham, A
    El Massry, AM
    Amer, A
    Gohar, YM
    LETTERS IN PEPTIDE SCIENCE, 2002, 9 (01): : 49 - 54
  • [47] Synthesis and Reactions of New Chiral Linear Carboxamides with an Incorporated Peptide Linkage Using Nalidixic Acid and Amino Acids as Starting Materials
    Khalifa, Nagy M.
    Naglah, Ahmed M.
    Al-Omar, Mohamed A.
    Abo-Ghalia, Mohamed H.
    Amr, Abd El-Galil E.
    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2014, 69 (03): : 351 - 361
  • [48] New ligand exchange chiral stationary phase for the liquid chromatographic resolution of α- and β-amino acids
    Hyun, MH
    Han, SC
    Whangbo, SH
    JOURNAL OF CHROMATOGRAPHY A, 2003, 992 (1-2) : 47 - 56
  • [49] Synthesis of new chiral building blocks for novel peptide nucleic acids
    Wu, J
    Xu, XY
    Liu, KL
    CHINESE JOURNAL OF CHEMISTRY, 2003, 21 (05) : 566 - 573
  • [50] Protonation-Assisted Conjugate Addition of Axially Chiral Enolates: Asymmetric Synthesis of Multisubstituted β-Lactams from α-Amino Acids
    Yoshimura, Tomoyuki
    Takuwa, Masatoshi
    Tomohara, Keisuke
    Uyama, Makoto
    Hayashi, Kazuhiro
    Yang, Pan
    Hyakutake, Ryuichi
    Sasamori, Takahiro
    Tokitoh, Norihiro
    Kawabata, Takeo
    CHEMISTRY-A EUROPEAN JOURNAL, 2012, 18 (48) : 15330 - 15336