Allergy to Peanuts imPacting Emotions And Life (APPEAL): the impact of peanut allergy on children, adolescents, adults and caregivers in France

被引:14
作者
Couratier, Pascale [1 ]
Montagne, Romain [2 ]
Acaster, Sarah [3 ]
Gallop, Katy [3 ]
Patel, Ram [4 ]
Vereda, Andrea [2 ]
Pouessel, Guillaume [5 ,6 ,7 ,8 ]
机构
[1] Assoc Francaise Prevent Allergies AFPRAL, 4 Pl Louis Armand La Tour Horloge, F-75012 Paris, France
[2] Aimmune Therapeut, 10 Eastbourne Terrace, London W2 6LG, England
[3] Acaster Lloyd Consulting Ltd, 16 Woburn Pl, London WC1H 0BS, England
[4] Brainsell Ltd, 4 Duke St, Richmond TW9 1HP, Surrey, England
[5] Childrens Hosp, Dept Pediat, F-59056 Roubaix, France
[6] Lille Univ, Pediat Pulmonol & Allergy Dept, CHU Lille, F-59000 Lille, France
[7] CHRU Lille, Hop Jeanne Flandre, Unite Pneumol & Allergol Pediat, 2 Ave Oscar Lambret, F-59037 Lille, France
[8] Univ Lille2, 2 Ave Oscar Lambret, F-59037 Lille, France
关键词
Peanut allergy; France; Clinical history; Diagnosis; Burden; Quality of life; QUALITY-OF-LIFE; HEALTH-RELATED QUALITY; FOOD ALLERGY; PATIENT; PARENTS; BURDEN;
D O I
10.1186/s13223-020-00481-7
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Background Peanut allergy (PA) has increased in developed countries and can have a dramatic effect on quality of life but data surrounding this is limited in France. Allergy to Peanuts imPacting Emotions And Life study (APPEAL) investigated the experience and impact of living with PA in France. Methods Respondents affected by PA directly (children aged 8-12 years, teenagers aged 13-17 years, or adults aged >= 18 years) or indirectly (caregiver) completed either an online questionnaire (APPEAL-1, N = 198), or provided in-depth interviews (APPEAL-2, N = 32). Quantitative data was evaluated using descriptive statistics. Qualitative data was analysed thematically, using MAXQDA software. Results Of 198 responders in APPEAL-1, 88% stated that PA affects their daily activities, and 74% felt isolated as a result of living with PA. Feelings of worry about exposure to peanuts on social occasions where food is involved was reported by 91%. A total of 44% reported some restrictions in their job options, 85% in socializing. Psychological impact of PA included responders feeling emotions of frustration (89%), uncertainty (87%), and stress (93%) and 93% reporting encountering instances of feeling different due to their PA. Main factors that drove PA impact included social activities and relationships; whereas main coping strategies to avoid peanuts included monitoring, communication and planning. Conclusion The analysis of French respondents from the APPEAL study demonstrates the impact and burden of PA on allergic children, teenagers, adults and their caregivers, and highlights the unmet need to be addressed.
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页数:11
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