Protein and RNA export from the nucleus

被引：118
作者：
Lei, EP
Silver, PA [1 ]
机构：
[1] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
[2] Dana Farber Canc Inst, Boston, MA 02115 USA
来源：
DEVELOPMENTAL CELL | 2002年 / 2卷 / 03期
关键词：
D O I：
10.1016/S1534-5807(02)00134-X
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The presence of the nuclear envelope necessitates the movement of proteins and RNAs between the nucleus and the cytoplasm. Elaborate cellular machinery exists to promote the nuclear transport of macromolecules. Recent advances in the field have illuminated our comprehension of both nuclear import and export as powerful means of gene regulation. As our appreciation of the importance of the process has grown, its study has matured, moving beyond the single cell to the entire organism. This review discusses basic mechanisms and regulation of protein, mRNA, and ribosome export with an emphasis on developmental examples.
引用
收藏
页码：261 / 272
页数：12
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