Adverse drug reactions among patients admitted with infectious diseases at a Brazilian hospital

被引：2

作者：

Saavedra, Pamela Alejandra ^{[1
]}

Milward de Azevedo Meiners, Micheline Marie ^{[2
]}

Lopes, Luciane Cruz ^{[3
]}

da Silva, Emilia Vitria ^{[2
]}

Mendonca da Silva, Dayde Lane ^{[1
]}

Noronha, Elza Ferreira ^{[4
]}

de Toledo, Maria Ines ^{[1
]}

机构：

[1] Univ Brasilia, Fac Ciencias Saude, Ceilandia, DF, Brazil

[2] Univ Brasilia, Fac Ceilandia, Ceilandia, DF, Brazil

[3] Univ Sorocaba, Programa Posgrad Ciencias Farmaceut, Sorocaba, SP, Brazil

[4] Univ Brasilia, Fac Med, Nucleo Med Trop, Brasilia, DF, Brazil

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2016年 / 49卷 / 06期

关键词：

Adverse drug reactions; Pharmacovigilance; Hospitals; EVENTS;

D O I：

10.1590/0037-8682-0238-2016

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Introduction: Despite the therapeutic benefits of drugs, adverse drug reactions (ADRs) occur. Method: We assessed a series of suspected ADRs identified from notifications and intensive monitoring of inpatients from March 2013 to March 2014. Results: Skin reactions predominated (31%). Systemic anti-infective agents were implicated in 16 (72%) reactions. Fifteen (68%) ADRs were classified as possible. The implicated drug was not correctly identified by the healthcare team in 12 cases. Conclusions: Some reactions were not correctly attributed to the causative drug(s), suggesting that the use of a validated evaluation method can promote successful identification of causal links between ADRs and drugs.

引用

页码：763 / 767

页数：5

共 19 条

[1] Adverse drug reaction monitoring: support for pharmacovigilance at a tertiary care hospital in Northern Brazil
Alves de Araujo Lobo, Marcia Germana
Botelho Pinheiro, Sandra Maria
Diaz Castro, Jose Gerley
Momente, Valeria Gomes
Pranchevicius, Maria-Cristina S.
[J]. BMC PHARMACOLOGY & TOXICOLOGY, 2013, 14
[2] [Anonymous], TRUV HLTH ANAL
[3] Aronson J.K., 2006, Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions
[4] Prevalence of hospital admission due to adverse drug reaction in Salvador, Bahia
Beisl Noblat, Antonio Carlos
Costa Beisl Noblat, Lucia Araujo
Kister de Toledo, Leonardo Augusto
Santos, Pablo de Moura
Guimaraes de Oliveira, Marcio Galvao
Tanajura, Gustavo Mustafa
Spinola, Silviana Ultchak
Madureira de Almeida, Jose Ricardo
[J]. REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 2011, 57 (01): : 42 - 45
[5] A study of agreement between the Naranjo algorithm and WHO-UMC criteria for causality assessment of adverse drug reactions
Belhekar, Mahesh N.
Taur, Santosh R.
Munshi, Renuka P.
[J]. INDIAN JOURNAL OF PHARMACOLOGY, 2014, 46 (01) : 117 - 120
[6] Adverse drug events in hospitals: a systematic review
Cano, Fabiola Giordani
Rozenfeld, Suely
[J]. CADERNOS DE SAUDE PUBLICA, 2009, 25 : S360 - S372
[7] Danza A, 2010, REV MED URUG, V26, P138
[8] Davies D M., 1998, Davies textbook of adverse drug reactions, V5th
[9] Ethnicity and adverse drug reactions - Personalised drug treatment is getting closer but will not replace good clinical judgment
Eliasson, E
[J]. BRITISH MEDICAL JOURNAL, 2006, 332 (7551): : 1163 - 1164
[10] Menezes FG, 2010, CONSCIENTIAE SAUDE, V9, P582

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