Effects of the volatile oil of Nigella sativa seeds on the uterine smooth muscle of rat and guinea pig

被引：52
作者：
Aqel, M
Shaheen, R
机构：
[1] College of Medicine, University of Jordan, Amman
来源：
JOURNAL OF ETHNOPHARMACOLOGY | 1996年 / 52卷 / 01期
关键词：
Nigella sativa; uterine horn; spontaneous movement; oxytocin;
D O I：
10.1016/0378-8741(95)01330-X
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The effects of the volatile oil of Nigella sativa seeds on the uterine smooth muscle of rats and guinea pigs was tested in vitro using isolated uterine horns. The volatile oil of Nigella sativa seeds inhibited the spontaneous movements of rat and guinea pig uterine smooth muscle and also the contractions induced by oxytocin stimulation. These effects were concentration-dependent and reversible by tissue washing. These data suggest that this volatile oil may have some antioxytocic potential.
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页码：23 / 26
页数：4
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