One-pot preparation of substituted pyrroles from α-diazocarbonyl compounds

被引：5
作者：
da Silva, Fernando de C. [1 ]
Fonseca, Mauricio G. [1 ]
Rianelli, Renata de S. [1 ]
Cunha, Anna C. [1 ]
de Souza, Maria C. B. V. [1 ]
Ferreira, Vitor F. [1 ]
机构：
[1] Univ Fed Fluminense, Dept Quim Organ, Inst Quim, BR-24020141 Niteroi, RJ, Brazil
来源：
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 4卷
关键词：
diazocarbonyl; dihydrofuran; one-pot synthesis; pyrrole;
D O I：
10.3762/bjoc.4.45
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In this work an efficient one-pot synthesis of substituted pyrroles 7a-n is described, which involves the in situ formation of dihydrofurans ethyl 5-butoxy-2-methyl-4,5-dihydrofuran-3-carboxylate (4), 1-(5-butoxy-2-methyl-4,5-dihydrofuran-3-yl)ethanone (5) and 5-butoxy-4,5-dihydrofuran-3-carbaldehyde (6) followed by reaction with primary amines.
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页数：4
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