Correlation between microdilution, Etest, and disk diffusion methods for antifungal susceptibility testing of fluconazole against Candida sp blood isolates

被引：4

作者：

Menezes, Everardo Albuquerque ^{[1
]}

de Vasconcelos Junior, Antonio Alexandre ^{[1
]}

Ferreira Angelo, Maria Rozzele ^{[2
]}

dos Santos Oliveira Cunha, Maria da Conceicao ^{[1
]}

Cunha, Francisco Afranio ^{[1
]}

机构：

[1] Univ Fed Ceara, Fac Farm, Dept Anal Clin & Toxicol, Lab Pesquisa Microbiol Leveduras, Fortaleza, CE, Brazil

[2] Hosp Fortaleza, Fortaleza, CE, Brazil

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2013年 / 46卷 / 01期

关键词：

Disk diffusion; Antifungal susceptibility; Fluconazole;

D O I：

10.1590/0037-868210502013

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Introduction: Antifungal susceptibility testing assists in finding the appropriate treatment for fungal infections, which are increasingly common. However, such testing is not very widespread. There are several existing methods, and the correlation between such methods was evaluated in this study. Methods: The susceptibility to fluconazole of 35 strains of Candida sp. isolated from blood cultures was evaluated by the following methods: microdilution, Etest, and disk diffusion. Results: The correlation between the methods was around 90%. Conclusions: The disk diffusion test exhibited a good correlation and can be used in laboratory routines to detect strains of Candida sp. that are resistant to fluconazole.

引用

页码：106 / 107

页数：2

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