TWO NEW ATISINE-TYPE C20-DITERPENOID ALKALOIDS FROM ACONITUM LEUCOSTOMUM

被引：13
作者：
Xu, Wenliang [1 ]
Chen, Lin [1 ,2 ,3 ]
Shan, Lianhai [1 ]
Gao, Feng [1 ]
Huang, Shuai [1 ]
Zhou, Xianli [1 ,2 ]
机构：
[1] Southwest Jiaotong Univ, Sch Life Sci & Engn, Chengdu 610031, Peoples R China
[2] Southwest Jiaotong Univ, Sch Mat Sci & Engn, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Peoples R China
[3] China West Normal Univ, Sch Chem & Chem Engn, Nanchong 637002, Peoples R China
来源：
HETEROCYCLES | 2016年 / 92卷 / 11期
基金：
中国国家自然科学基金;
关键词：
DITERPENOID ALKALOIDS; CRYSTAL; VEATCHINE; AJACONINE; CHLORIDE; RING;
D O I：
10.3987/COM-16-13556
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Two new atisine-type C-20-diterpenoid alkaloids, leucostomine A (1) and leucostomine B (2) were isolated from the root of Aconitum leucostomum. Their structures were determined by spectroscopic methods including 1D-, 2D-NMR, and HR-ESI-MS.
引用
收藏
页码：2059 / 2065
页数：7
相关论文
共 23 条
  • [1] Crystal structure, phytochemical study and enzyme inhibition activity of Ajaconine and Delectinine
    Ahmad, Shujaat
    Ahmad, Hanif
    Khan, Hidayat Ullah
    Shahzad, Adnan
    Khan, Ezzat
    Shah, Syed Adnan Ali
    Ali, Mumtaz
    Wadud, Abdul
    Ghufran, Mehreen
    Naz, Humera
    Ahmad, Manzoor
    [J]. JOURNAL OF MOLECULAR STRUCTURE, 2016, 1123 : 441 - 448
  • [2] Hetisane-type diterpenoid alkaloids
    Bessonova, IA
    Saidkhodzhaeva, SA
    [J]. CHEMISTRY OF NATURAL COMPOUNDS, 2000, 36 (05) : 419 - 477
  • [3] DENG W, 1986, Heterocycles (Tokyo), V24, P869
  • [4] DESAI HK, 1993, HETEROCYCLES, V36, P1081
  • [5] Gao LM, 2004, HETEROCYCLES, V63, P1181
  • [6] HAO XJ, 1987, CHEM PHARM BULL, V35, P1670
  • [7] C-13 NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY OF ATISINE AND VEATCHINE-TYPE C-20-DITERPENOID ALKALOIDS FROM ACONITUM AND GARRYA SPECIES
    MODY, NV
    PELLETIER, SW
    [J]. TETRAHEDRON, 1978, 34 (16) : 2421 - 2431
  • [8] EPIMERIZATION AND ISOMERIZATION IN C20 DITERPENOID ALKALOIDS - CRYSTAL AND MOLECULAR-STRUCTURES OF ATISINIUM CHLORIDE, DIHYDROATISIN, ISOATISINE, AND VEATCHINE
    PELLETIER, SW
    DECAMP, WH
    MODY, NV
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (25) : 7976 - 7987
  • [9] NMR STUDIES OF DITERPENE ALKALOIDS
    PELLETIER, SW
    OELTMANN, TN
    [J]. TETRAHEDRON, 1968, 24 (04) : 2019 - +
  • [10] UNUSUAL REARRANGEMENT OF AJACONINE - EXAMPLE OF A DIS-FAVORED 5-ENDO-TRIGONAL RING-CLOSURE
    PELLETIER, SW
    MODY, NV
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1979, 101 (02) : 492 - 494
123