Hepatitis E Virus: What Transplant Physicians Should Know

被引：42

作者：

Kamar, N. ^{[1
,2
,3
]}

Legrand-Abravanel, F. ^{[2
,3
,4
]}

Izopet, J. ^{[2
,3
,4
]}

Rostaing, L. ^{[1
,2
,3
]}

机构：

[1] CHU Rangueil, Dept Nephrol Dialysis & Organ Transplantat, F-31054 Toulouse, France

[2] CHU Purpan, INSERM, U1043, IFR BMT, Toulouse, France

[3] Univ Toulouse 3, F-31062 Toulouse, France

[4] CHU Purpan, Dept Virol, Toulouse, France

来源：

AMERICAN JOURNAL OF TRANSPLANTATION | 2012年 / 12卷 / 09期

关键词：

Chronic infection; cirrhosis; extra-hepatic symptoms; hepatitis E virus; ribavirin; LIVER-TRANSPLANT; BLOOD-DONORS; E INFECTION; RECIPIENTS; KIDNEY; REACTIVATION; ANTIBODIES; RIBAVIRIN; THERAPY; PATIENT;

D O I：

10.1111/j.1600-6143.2012.04078.x

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Hepatitis E virus (HEV) infection is an underdiagnosed disease in the developed world. In pediatric and adult organ transplant patients HEV infection can cause chronic hepatitis, which can lead to cirrhosis. Extra-hepatic manifestations, such as neurological symptoms and kidney injury, have been also reported in transplant patients. In this comprehensive minireview, we summarize the current knowledge on HEV infection in transplant patients, that is, its prevalence, incidence, natural history and therapy.

引用

页码：2281 / 2287

页数：7

共 43 条

[41] Liver transplant from a donor with occult HEV infection induced chronic hepatitis and cirrhosis in the recipient [J].