Changing Epidemiology of Nontuberculous Mycobacterial Lung Diseases in a Tertiary Referral Hospital in Korea between 2001 and 2015

被引:51
作者
Ko, Ryoung-Eun [1 ]
Moon, Seong Mi [1 ]
Ahn, Soohyun [2 ]
Jhun, Byung Woo [1 ]
Jeon, Kyeongman [1 ]
Kwon, O. Jung [1 ]
Huh, Hee Jae [3 ]
Ki, Chang-Seok [3 ]
Lee, Nam Yong [3 ]
Koh, Won-Jung [1 ]
机构
[1] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Med,Div Pulmonol & Crit Care Med, 81 Irwon Ro, Seoul, South Korea
[2] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Res Inst Future Med,Stat & Data Ctr, Seoul, South Korea
[3] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Lab Med & Genet, Seoul, South Korea
基金
新加坡国家研究基金会;
关键词
Nontuberculous Mycobacteria; Mycobacterium avium Complex; Mycobacterium abscessus; Mycobacterium kansasii; Epidemiology; Republic of Korea; CLINICAL-SIGNIFICANCE; DIAGNOSIS; DIFFERENTIATION; INTRACELLULARE; BRONCHIECTASIS; AVIUM;
D O I
10.3346/jkms.2018.33.e65
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This study investigated the changes in the major etiologic organisms and clinical phenotypes of nontuberculous mycobacterial lung disease (NTM-LD) over a recent 15-year period in Korea. The increase of number of patients with NTM-LD was primarily due to an increase of Mycobacterium avium complex (MAC) lung disease (LD). Among MAC cases, the proportion of M. avium increased compared with M. intracellulare, whereas the incidence of M. abscessus complex and M. kansasii LD remained relatively stable. The proportion of cases of the nodular bronchiectatic form increased compared with the fibrocavitary form of NTM-LD.
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页数:6
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