Herpes reactivation after the injection of hyaluronic acid dermal filler A case report and review of literature

被引：7

作者：

Wang, Chenyu ^{[1
,2
]}

Sun, Tianyu ^{[3
]}

Yu, Nanze ^{[1
,2
]}

Wang, Xiaojun ^{[1
,2
]}

机构：

[1] Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Plast Surg, Beijing 100730, Peoples R China

[2] Chinese Acad Med Sci, Beijing 100730, Peoples R China

[3] Univ Oxford, Radcliffe Dept Med, Nuffield Div Clin Lab Sci, Oxford OX3 9DU, England

来源：

MEDICINE | 2020年 / 99卷 / 24期

关键词：

cosmetic injection; herpes reactivation; hyaluronic acid; INFECTIONS;

D O I：

10.1097/MD.0000000000020394

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction: Hyaluronic acid injections is relatively safe with little risk of complications. Although herpes reactivation after the injection of hyaluronic acid is rare, it produces quite a huge pressure and panic on patients. Quite a lot cosmetic practitioners have no awareness of preventing, diagnosing, and giving correct treatment in time due to lack of experience. Patient concerns: A 24-year-old woman presented with erythema, crusted papules, pain and swelling on the nose after receiving the injection of hyaluronic acid. A swab of the discharge fluid was obtained for bacterial and viral culture, showing positive for herpes simplex virus. Diagnosis: The patient was diagnosed as herpes reactivation after the injection of hyaluronic acid. Interventions: The patient underwent antiviral therapy with acyclovir 400mg, 3 times daily for seven days. Outcomes: After a week of antiviral treatment, the clinical signs improved. Conclusion: Herpes reactivation after the injection of hyaluronic acid is quite rare but needed sufficient attention of cosmetic practitioners to make the proper diagnosis, prevention and treatment.

引用

页数：3

共 17 条

[1] Resistant and Recurrent Late Reaction to Hyaluronic Acid-Based Gel [J].

Artzi, Ofir ;

Loizides, Christoforos ;

Verner, Ines ;

Landau, Marina .

DERMATOLOGIC SURGERY, 2016, 42 (01) :31-37

[2] In vitro evaluation of antiviral and virucidal activity of a high molecular weight hyaluronic acid [J].

Cermelli, Claudio ;

Cuoghi, Alessandro ;

Scuri, Monica ;

Bettua, Clotilde ;

Neglia, Rachele G. ;

Ardizzoni, Andrea ;

Blasi, Elisabetta ;

Iannitti, Tommaso ;

Palmieri, Beniamino .

VIROLOGY JOURNAL, 2011, 8

[3] The treatment of herpes simplex infections - An evidence-based review [J].

Cernik, Christina ;

Gallina, Kelly ;

Brodell, Robert T. .

ARCHIVES OF INTERNAL MEDICINE, 2008, 168 (11) :1137-1144

[4] Cutaneous Infections Caused by Herpesviridae A Review [J].

Chisholm, Cary ;

Lopez, Lisa .

ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 2011, 135 (10) :1357-1362

[5] Understanding, avoiding, and managing dermal filler complications [J].

Cohen, Joel L. .

DERMATOLOGIC SURGERY, 2008, 34 (01) :S92-S99

[6] Commentary on Delayed Onset Nodules Secondary to a Smooth Cohesive 20 mg/mL Hyaluronic Acid Filler: Cause and Management [J].

Del Campo, Roberta ;

Mandy, Stephen .

DERMATOLOGIC SURGERY, 2015, 41 (08) :940-941

[7] Angioedema-type swelling and herpes simplex virus reactivation following hyaluronic acid injection for lip augmentation [J].

Dougherty, Alexis L. ;

Rashid, Rashid M. ;

Bangert, Carolyn A. .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2011, 65 (01) :E21-E22

[8] Modeling the pathology, immune responses, and kinetics of HSV-1 replication in the lip scarification model [J].

Egan, Kevin P. ;

Allen, Alexander G. ;

Wigdahl, Brian ;

Jennings, Stephen R. .

VIROLOGY, 2018, 514 :124-133

[9] Lip Nodules Caused by Hyaluronic Acid Filler Injection: Report of Three Cases [J].

Farahani S.S. ;

Sexton J. ;

Stone J.D. ;

Quinn K. ;

Woo S.-B. .

Head and Neck Pathology, 2012, 6 (1) :16-20

[10]

Food and Drug Administration, 2003, SUMM SAF EFF DAT

← 1 2 →