Vancomycin resistance in gram-positive cocci

被引：636

作者：

Courvalin, P ^{[1
]}

机构：

[1] Inst Pasteur, Unite Agents Antibacteriens, F-75724 Paris, France

来源：

CLINICAL INFECTIOUS DISEASES | 2006年 / 42卷

关键词：

D O I：

10.1086/491711

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The first vancomycin-resistant clinical isolates of Enterococcus species were reported in Europe in 1988. Similar strains were later detected in hospitals on the East Coast of the United States. Since then, vancomycin-resistant enterococci have spread with unexpected rapidity and are now encountered in hospitals in most countries. This article reviews the mode of action and the mechanism of bacterial resistance to glycopeptides, as exemplified by the VanA type, which is mediated by transposon Tn1546 and is widely spread in enterococci. The diversity, regulation, evolution, and recent dissemination of methicillin-resistant Staphylococcus aureus are then discussed.

引用

页码：S25 / S34

页数：10

共 49 条

[1]

[Anonymous], 2002, MMWR MORB MORTAL WKL, V51, P565

[2] vanC cluster of vancomycin-resistant Enterococcus gallinarum BM4174 [J].

Arias, CA ;

Courvalin, P ;

Reynolds, PE .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (06) :1660-1666

[3] The VanS sensor negatively controls VanR-mediated transcriptional activation of glycopeptide resistance genes of Tn1546 and related elements in the absence of induction [J].

Arthur, M ;

Depardieu, F ;

Gerbaud, G ;

Galimand, M ;

Leclercq, R ;

Courvalin, P .

JOURNAL OF BACTERIOLOGY, 1997, 179 (01) :97-106

[4] Quantitative analysis of the metabolism of soluble cytoplasmic peptidoglycan precursors of glycopeptide-resistant enterococci [J].

Arthur, M ;

Depardieu, F ;

Reynolds, P ;

Courvalin, P .

MOLECULAR MICROBIOLOGY, 1996, 21 (01) :33-44

[5] Requirement of the VanY and VanX D,D-peptidases for glycopeptide resistance in enterococci [J].

Arthur, M ;

Depardieu, F ;

Cabanié, L ;

Reynolds, P ;

Courvalin, P .

MOLECULAR MICROBIOLOGY, 1998, 30 (04) :819-830

[6] THE VANS-VANR 2-COMPONENT REGULATORY SYSTEM CONTROLS SYNTHESIS OF DEPSIPEPTIDE PEPTIDOGLYCAN PRECURSORS IN ENTEROCOCCUS-FAECIUM BM4147 [J].

ARTHUR, M ;

MOLINAS, C ;

COURVALIN, P .

JOURNAL OF BACTERIOLOGY, 1992, 174 (08) :2582-2591

[7] CHARACTERIZATION OF TN1546, A TN3-RELATED TRANSPOSON CONFERRING GLYCOPEPTIDE RESISTANCE BY SYNTHESIS OF DEPSIPEPTIDE PEPTIDOGLYCAN PRECURSORS IN ENTEROCOCCUS-FAECIUM BM4147 [J].

ARTHUR, M ;

MOLINAS, C ;

DEPARDIEU, F ;

COURVALIN, P .

JOURNAL OF BACTERIOLOGY, 1993, 175 (01) :117-127

[8] Glycopeptide resistance in enterococci [J].

Arthur, M ;

Reynolds, P ;

Courvalin, P .

TRENDS IN MICROBIOLOGY, 1996, 4 (10) :401-407

[9] Emergence of vancomycin-resistant enterococci in Australia: Phenotypic and genotypic characteristics of isolates [J].

Bell, JM ;

Paton, JC ;

Turnidge, J .

JOURNAL OF CLINICAL MICROBIOLOGY, 1998, 36 (08) :2187-2190

[10]

BERG CM, 1995, MOBILE GENETIC ELEME, P38

← 1 2 3 4 5 →