A environmentally friendly reversed-phase liquid chromatography method for phthalates determination in nail cosmetics

被引：67
作者：
De Orsi, D
Gagliardi, L
Porrà, R
Berri, S
Chimenti, P
Granese, A
Carpani, I
Tonelli, D
机构：
[1] Dipartimento Chim Fis & Inorgan, I-40136 Bologna, Italy
[2] Ist Super Sanita, Dipartimento Farm, I-00161 Rome, Italy
[3] Univ Roma La Sapienza, Dipartimento Chim & Tecnol Sostanze Biologicament, Rome, Italy
来源：
ANALYTICA CHIMICA ACTA | 2006年 / 555卷 / 02期
关键词：
phthalates; HPLC; cosmetic products; quality control; green analytical chemistry;
D O I：
10.1016/j.aca.2005.09.029
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A simple and rapid analytical method was developed for the determination of phthalates, usually employed in nail cosmetic products. The method is based on an ultrasonic extraction of the sample with ethanol-water (90: 10, v/v) followed by HPLC separation and quantitation. HPLC was carried out using a C18 column and spectrophotometric detection at 254 nm. A linear gradient elution was performed with ethanol-water starting from 50 to 95% ethanol in 30 min. Standard calibration curves were linear for all the analytes over the concentration range 5-200 mu g ml(-1) with LOD values of about 0.5 mu g ml(-1). The proposed green analytical method has been successfully applied for the analysis of commercial samples in order to check the presence of phthalates and to determine their concentration. (c) 2005 Elsevier B.V. All rights reserved.
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收藏
页码：238 / 241
页数：4
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