Malignant fibrous histiocytoma after allogeneic bone marrow transplantation

被引:1
作者
Vela-Ojeda, J [1 ]
de León, LD [1 ]
Tripp-Villanueva, F [1 ]
Sanchez-Cortés, E [1 ]
Ayala-Sanchez, M [1 ]
Esparza, MAGR [1 ]
Rosas-Cabral, A [1 ]
Gonzalez-Llaven, J [1 ]
机构
[1] IMSS, Ctr Med Nacl La Raza, Hosp Especialidades, Mexico City 07001, DF, Mexico
关键词
malignant fibrous histiocytoma; bone marrow transplantation; secondary cancer;
D O I
10.1038/sj.bmt.1701919
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A 24-year-old woman with CML underwent allogeneic BMT in August 1995 from a one-antigen HLA mismatched brother. Conditioning included BuCy2 and CsA and MTX were used to prevent GVHD. In July 1997 she developed right leg pain, lytic bone lesions of distal femur and a solid mass of soft tissue. Histological diagnosis of malignant fibrous histiocytoma was made. Despite treatment with surgery and chemotherapy (doxorubicin and ifosfamide), the patient died 1 year later with local recurrence of the tumor and liver, lung and brain metastases. The CML was in CR.
引用
收藏
页码:1029 / 1031
页数:3
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