Use of the 46/1 haplotype to model JAK2V617F clonal architecture in PV patients: clonal evolution and impact of IFNα treatment

被引：13
作者：
Hasan, S. [1 ,2 ,3 ]
Cassinat, B. [4 ]
Droin, N. [1 ,2 ,3 ]
Le Couedic, J. P. [1 ,2 ,3 ]
Favale, F. [1 ,2 ,3 ]
Monte-Mor, B. [1 ,2 ,3 ]
Lacout, C. [1 ,2 ,3 ]
Fontenay, M. [5 ]
Dosquet, C. [4 ]
Chomienne, C. [4 ,6 ]
Solary, E. [1 ,2 ,3 ]
Villeval, J. L. [1 ,2 ,3 ]
Casadevall, N. [1 ,7 ]
Kiladjian, J. J. [8 ]
Vainchenker, W. [1 ,2 ,3 ]
Plo, I. [1 ,2 ,3 ]
机构：
[1] INSERM, UMR 1009, Lab Excellence GR Ex, Villejuif, France
[2] Univ Paris 11, Inst Gustave Roussy, UMR 1009, Villejuif, France
[3] Inst Gustave Roussy, Villejuif, France
[4] Hop St Louis, AP HP, Serv Biol Cellulaire, Paris, France
[5] Hop Cochin, AP HP, Serv Hematol Biol, F-75674 Paris, France
[6] Univ Paris Diderot, Sorbonne Paris Cite, Paris, France
[7] Hop St Antoine, AP HP, Hematol Lab, F-75571 Paris, France
[8] Hop St Louis, AP HP, Ctr Invest Clin, Paris, France
来源：
LEUKEMIA | 2014年 / 28卷 / 02期
关键词：
TYROSINE KINASE JAK2; POLYCYTHEMIA-VERA; MYELOPROLIFERATIVE NEOPLASMS; ESSENTIAL THROMBOCYTHEMIA; HEMATOPOIETIC STEM; MUTATION; DISORDERS; JAK2V617F; CELLS;
D O I：
10.1038/leu.2013.303
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：460 / 463
页数：5
相关论文
共 50 条
  • [31] Concomitant BCR-ABL1 Translocation and JAK2V617F Mutation in Three Patients with Myeloproliferative Neoplasms
    Hummel, Jennifer M.
    Kletecka, M. Carmen Frias
    Sanks, Jennifer K.
    Chiselite, Mihaela D.
    Roulston, Diane
    Smith, Lauren B.
    Czuchlewski, David R.
    Elenitoba-Johnson, Kojo S. J.
    Lim, Megan S.
    DIAGNOSTIC MOLECULAR PATHOLOGY, 2012, 21 (03) : 176 - 183
  • [32] Anti-inflammatory cytokines hepatocyte growth factor and interleukin-11 are over-expressed in Polycythemia vera and contribute to the growth of clonal erythroblasts independently of JAK2V617F
    Boissinot, M.
    Cleyrat, C.
    Vilaine, M.
    Jacques, Y.
    Corre, I.
    Hermouet, S.
    ONCOGENE, 2011, 30 (08) : 990 - 1001
  • [33] Data-driven analysis of JAK2V617F kinetics during interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms
    Pedersen, Rasmus K.
    Andersen, Morten
    Knudsen, Trine A.
    Sajid, Zamra
    Gudmand-Hoeyer, Johanne
    Dam, Marc J. B.
    Skov, Vibe
    Kjaer, Lasse
    Ellervik, Christina
    Larsen, Thomas S.
    Hansen, Dennis
    Pallisgaard, Niels
    Hasselbalch, Hans C.
    Ottesen, Johnny T.
    CANCER MEDICINE, 2020, 9 (06): : 2039 - 2051
  • [34] Interleukin-1 contributes to clonal expansion and progression of bone marrow fibrosis in JAK2V617F-induced myeloproliferative neoplasm
    Rahman, Mohammed Ferdous-Ur
    Yang, Yue
    Le, Bao T.
    Dutta, Avik
    Posyniak, Julia
    Faughnan, Patrick
    Sayem, Mohammad A.
    Aguilera, Nadine S.
    Mohi, Golam
    NATURE COMMUNICATIONS, 2022, 13 (01)
  • [35] Impact of JAK2V617F mutation on thrombosis and myeloid transformation in essential thrombocythemia: a multivariate analysis by Cox regression in 141 patients
    Chim, C. S.
    Sim, J. P.
    Chan, C. C.
    Kho, B. C.
    Chan, J. C.
    Wong, L. G.
    Law, M.
    Liang, R.
    Kwong, Y. L.
    HEMATOLOGY, 2010, 15 (04) : 187 - 192
  • [36] Impact of JAK2V617F Mutation on Coagulation Function Tests and Inflammatory Markers in Sudanese Patients with Essential Thrombocythemia
    Elbager, Sahar G.
    Bayoumi, Magdi A.
    Lai, Mei I.
    Tohit, Eusni Rahayu Mohd
    Dowd, Amar A.
    BRITISH JOURNAL OF HAEMATOLOGY, 2021, 193 : 116 - 117
  • [37] Impact of CALR and JAK2V617F Mutations on Clinical Course and Disease Outcomes in Essential Thrombocythemia: A Multicenter Retrospective Study in Turkish Patients
    Ozdemir, Zehra Narli
    Ipek, Yildiz
    Patir, Puesem
    Ermis, Goezde
    Ciftciler, Rafiye
    Ozmen, Deniz
    Baysal, Mehmet
    Gursoy, Vildan
    Yildizhan, Esra
    Guven, Serkan
    Ercan, Tarik
    Elibol, Tayfun
    Mersin, Sinan
    Genc, Eylem
    Davulcu, Eren Arslan
    Karakus, Volkan
    Erkut, Nergiz
    Gunes, Guersel
    Kucukkaya, Reyhan Diz
    Eskazan, Ahmet Emre
    TURKISH JOURNAL OF HEMATOLOGY, 2024, 41 (01) : 26 - 36
  • [38] ASXL1 and JAK2V617F gene mutation screening in Iranian patients with chronic myeloid leukemia
    Valikhani, Amir
    Poopak, Behzad
    Ferdowsi, Shirin
    Azizi Tabesh, Ghasem
    Ghaffari, Seyed H.
    Saraf Kazeruoni, Ehsan
    Rezaei, Negar
    Farshchi, Alireza
    Amirizadeh, Naser
    ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2017, 13 (02) : E41 - E47
  • [39] The impact of JAK2V617F mutation on different types of thrombosis risk in patients with essential thrombocythemia: a meta-analysis
    Youwen Qin
    Xiaorui Wang
    Chuxian Zhao
    Chun Wang
    Yining Yang
    International Journal of Hematology, 2015, 102 : 170 - 180
  • [40] MYB deregulation from a EWSR1-MYB fusion at leukemic evolution of a JAK2V617F positive primary myelofibrosis
    Pierini, Tiziana
    Di Giacomo, Danika
    Pierini, Valentina
    Gorello, Paolo
    Barba, Gianluca
    Fernandez, Anair Graciela Lema
    Pellanera, Fabrizia
    Iannotti, Tamara
    Falzetti, Franca
    La Starza, Roberta
    Mecucci, Cristina
    MOLECULAR CYTOGENETICS, 2016, 9
12345