Agreement between frequency-doubling technology perimetry and Heidelberg retinal tomography 3

To compare Heidelberg retinal tomography (HRT) 3 and frequency-doubling technology (FDT) perimetry for diagnosis of glaucoma. One eye of each of 117 patients was randomly chosen. The eyes were imaged by HRT3 and tested by FDT. The pattern standard deviation (PSD) and global glaucoma probability score (GPS) were selected as representative output, and sensitivity, specificity, positive predictive value, and negative predictive value determined for each. The agreement between the 2 diagnostic methods was analyzed. The sensitivity and specificity of HRT3 and FDT perimetry for PSD (65.4 and 62.7 %, respectively) and for GPS (69.2 and 62.7 %, respectively) were similar, as were the positive predictive values (PSD 40.5 %, GPS 41.9 %). However, the 2 methods had only slight diagnostic agreement (kappa = 0.112), and this was not significant (P = 0.281). FDT perimetry and HRT3 had no significant diagnostic agreement. Thus, the results from both examinations should be considered when determining diagnosis of glaucoma.