Highly Porous Chitosan Beads Embedded with Silver-Graphene Oxide Nanocomposites for Antibacterial Application

被引:0
作者
Chook, Soon Wei [1 ]
Chia, Chin Hua [1 ]
Kaco, Hatika [1 ]
Zakaria, Sarani [1 ]
Huang, Nay Ming [2 ]
Neoh, Hui Min [3 ]
机构
[1] Univ Kebangsaan Malaysia, Sch Appl Phys, Fac Sci & Technol, Bioresources & Biorefinery Lab, Ukm Bangi 43600, Selangor Darul, Malaysia
[2] Univ Malaya, Dept Phys, Fac Sci, Kuala Lumpur 50603, Federal Territo, Malaysia
[3] Univ Kebangsaan Malaysia, UKM Med Mol Biol Inst, Kuala Lumpur 56000, Malaysia
来源
SAINS MALAYSIANA | 2016年 / 45卷 / 11期
关键词
Antibacterial; chitosan; silver-graphene oxide nanocomposites; silver nanoparticles; NANOPARTICLES; CHITIN;
D O I
暂无
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Incorporation of silver nanomaterial into polymer matrix can further accomplished their potential usage in real life applications. In our previous study, silver nanoparticles (AgNPs) and silver-graphene oxide nanocomposites (AgGO) were prepared via a rapid microwave-assisted method. Hereby, the as-synthesized AgNPs or AgGO was dispersed in a chitosan solution. Subsequently, the resultant mixture solution was further coagulated in a coagulation bath containing sodium hydroxide via a neutralization process. This resulted in the formation of spherical-shaped chitosan beads. The structure of the beads showed that the chitosan beads embedded with AgGO exhibited a more porous structure as compared to the plain chitosan beads. Furthermore, the chitosan beads containing AgNPs or AgGO were tested for their antibacterial activity against Escherichia coli and Staphylococcus aureus. The antibacterial results indicated that the silver nanomaterial contained chitosan beads could effectively inhibit the growth of both E. coli and S. aureus as compared to the bare chitosan beads. The produced chitosan nanocomposite envisioned that can be potentially employed for water disinfection purpose.
引用
收藏
页码:1663 / 1667
页数:5
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