A novel application of a [3+2] cycloaddition reaction for the synthesis of the piperazinone rings of pseudotheonamides A1 and A2

被引：19

作者：

Gurjar, MK ^{[1
]}

Karmakar, S ^{[1
]}

Mohapatra, DK ^{[1
]}

Phalgune, UD ^{[1
]}

机构：

[1] Natl Chem Lab, Pune 411008, Maharashtra, India

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 10期

关键词：

azides; enamines; olefins; stereoselective; Dess-Martin reagents;

D O I：

10.1016/S0040-4039(02)00133-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel approach to synthesize the piperazinone ring system of pseudotheonamide A(1) and A(2) is described. The key step is the intramolecular [3+2] cycloaddition reaction of a suitably orientated azide and an alpha,beta-unsaturated ester. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1897 / 1900

页数：4

共 40 条

[1] BETA-KETONITRILE-DERIVED PROTECTING GROUPS OF THE AMINO FUNCTION - SYNTHESIS OF AMINO-ALCOHOLS [J].