Design and Custom Fabrication of a Smart Temperature Sensor for an Organ-on-a-chip Platform

被引：0

作者：

Ponte, Ronaldo ^{[1
]}

Giagka, Vasiliki ^{[1
,2
]}

Serdijn, Wouter A. ^{[1
]}

机构：

[1] Delft Univ Technol, Fac EEMCS, Dept Microelect, Sect Bioelect, Delft, Netherlands

[2] Fraunhofer Inst Reliabil & Microintegrat IZM, Technol Bioelect Grp, Berlin, Germany

来源：

2018 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE (BIOCAS): ADVANCED SYSTEMS FOR ENHANCING HUMAN HEALTH | 2018年

关键词：

Smart temperature sensor; organ-on-a-chip; time-mode signal-processing; IC MEMS co-design;

D O I：

暂无

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

This paper reports on the design and fabrication of a time-mode signal-processing in situ temperature sensor customized for an organ-on-a-chip (OOC) application. The circuit was fabricated using an in-house integrated circuit (IC) technology that requires only seven lithographic steps and is compatible with MEMS fabrication process. The proposed circuit is developed to provide the first out-of-incubator temperature monitoring of cell cultures on an OOC platform in a monolithic fabrication. Measurement results on wafer reveal a temperature measurement resolution of less than +/- 0.2 degrees C (3 sigma) and a maximum nonlinearity error of less than 0.3% across a temperature range from 25 degrees C to 100 degrees C.

引用

页码：667 / 670

页数：4

共 28 条

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