Dehydrogenative cyclocondensation of aldehydes, alkynes, and dialkylsilanes

被引：47

作者：

Baxter, Ryan D. ^{[1
]}

Montgomery, John ^{[1
]}

机构：

[1] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 30期

关键词：

D O I：

10.1021/ja803774s

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The nickel-catalyzed coupling of aldehydes, alkynes, and dialkylsilanes results in an unusual dehydrogenative cyclocondensation process to afford five-membered silacyclic products. The process allows dialkylsilanes to serve as a silylene synthetic equivalent. A mechanistic pathway for the process involving the formation of an aldehyde/alkyne-derived nickel metallacycle followed by sequential sigma-bond metathesis processes involving the two Si-H bonds has been proposed.

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页码：9662 / +

页数：3

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