Rhodium-catalyzed asymmetric ring-opening alkynylation of azabenzonorbornadienes

被引：76

作者：

Nishimura, Takahiro ^{[1
]}

Tsurumaki, Eiji ^{[1
]}

Kawamoto, Takahiro ^{[1
]}

Guo, Xun-Xiang ^{[1
]}

Hayashi, Tamio ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Sci, Dept Chem, Sakyo Ku, Kyoto 6068502, Japan

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 18期

关键词：

D O I：

10.1021/ol801549t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Asymmetric ring-opening alkynylation of meso-azabenzonorbornadienes with (triisopropylsilyl)acetylene giving 2-alkynyl-1-aminodihydronaphthalenes took place in high yields with high enantioselectivity in the presence of a rhodium/(R)-DTBM-segphos catalyst.

引用

页码：4057 / 4060

页数：4

共 60 条

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