Antioxidant-Based Medicinal Properties of Stingless Bee Products: Recent Progress and Future Directions

被引:88
作者
Al-Hatamleh, Mohammad A., I [1 ]
Boer, Jennifer C. [2 ]
Wilson, Kirsty L. [2 ]
Plebanski, Magdalena [2 ]
Mohamud, Rohimah [1 ,3 ]
Mustafa, Mohd Zulkifli [3 ,4 ]
机构
[1] Univ Sains Malaysia, Sch Med Sci, Dept Immunol, Kubang Kerian 16150, Kelantan, Malaysia
[2] RMIT Univ, Sch Hlth & Biomed Sci, Translat Immunol & Nanotechnol Unit, Bundoora, Vic 3083, Australia
[3] Hosp Univ Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia
[4] Univ Sains Malaysia, Sch Med Sci, Dept Neurosci, Kubang Kerian 16150, Kelantan, Malaysia
关键词
stingless bee; meliponines; honey; propolis; natural products; phenolic compounds; flavonoids; antioxidants; PHENOLIC-COMPOUNDS; HONEY-BEES; ANTIMICROBIAL ACTIVITY; IN-VITRO; PHYSICOCHEMICAL PROFILES; GUT MICROBIOTA; TRIGONA SPP; GEN; NOV; PROPOLIS; CANCER;
D O I
10.3390/biom10060923
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Stingless bees are a type of honey producers that commonly live in tropical countries. Their use for honey is being abandoned due to its limited production. However, the recent improvements in stingless bee honey production, particularly in South East Asia, have brought stingless bee products back into the picture. Although there are many stingless bee species that produce a wide spread of products, known since old eras in traditional medicine, the modern medical community is still missing more investigational studies on stingless bee products. Whereas comprehensive studies in the current era attest to the biological and medicinal properties of honeybee (Apis mellifera) products, the properties of stingless bee products are less known. This review highlights for the first time the medicinal benefits of stingless bee products (honey, propolis, pollen and cerumen), recent investigations and promising future directions. This review emphasizes the potential antioxidant properties of these products that in turn play a vital role in preventing and treating diseases associated with oxidative stress, microbial infections and inflammatory disorders. Summarizing all these data and insights in one manuscript may increase the commercial value of stingless bee products as a food ingredient. This review will also highlight the utility of stingless bee products in the context of medicinal and therapeutic properties, some of which are yet to be discovered.
引用
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页码:1 / 28
页数:28
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