Induction Therapy for Newly Diagnosed Multiple Myeloma

被引：9

作者：

Lonial, Sagar ^{[1
]}

San Miguel, Jesus F. ^{[2
,3
]}

机构：

[1] Emory Univ, Winship Canc Inst, Dept Hematol & Med Oncol, Atlanta, GA 30322 USA

[2] Hosp Univ Salamanca, Serv Hematol, IBMCC USAL CSIC, Salamanca, Spain

[3] IBSAL, Salamanca, Spain

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2013年 / 11卷 / 01期

关键词：

STEM-CELL TRANSPLANTATION; THALIDOMIDE PLUS DEXAMETHASONE; HIGH-DOSE CHEMOTHERAPY; ELDERLY-PATIENTS; PHASE-III; INITIAL THERAPY; BORTEZOMIB INDUCTION; COMBINATION THERAPY; CONSENSUS STATEMENT; RESPONSE RATES;

D O I：

10.6004/jnccn.2013.0005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Treatment options for patients with newly diagnosed myeloma have evolved significantly over the past 10 years. Although response rates after induction for older or younger patients were limited, with few patients achieving complete remission, more recent combinations have cleared the way for major response and even complete remissions after induction therapy. As a consequence of these changes, patients are now achieving more durable and longer remissions, which have ultimately improved overall survival for patients with myeloma. The age-appropriate use of induction therapy, autologous transplant, and maintenance therapy, all keeping in mind the specific genetic risk group of a given patient, requires a long-term treatment plan for each patient defined early in the treatment course. (JNCCN 2013;11:19-28)

引用

页码：19 / 28

页数：10

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