Effect of pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of pravastatin)

被引：71

作者：

Masumoto, A ^{[1
]}

Hirooka, Y ^{[1
]}

Hironaga, K ^{[1
]}

Eshima, K ^{[1
]}

Setoguchi, S ^{[1
]}

Egashira, K ^{[1
]}

Takeshita, A ^{[1
]}

机构：

[1] Kyushu Univ, Grad Sch Med Sci, Dept Cardiovasc Med, Higashi Ku, Fukuoka 8128582, Japan

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2001年 / 88卷 / 11期

基金：

日本学术振兴会;

关键词：

D O I：

10.1016/S0002-9149(01)02090-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We examined the effect of pravastatin on endothelial function in patients with coronary artery disease but without hypercholesterolemia. Our results suggest that short-term treatment with pravastatin improves impaired endothelial function in patients by mediating the increase in nitric oxide production.

引用

页码：1291 / +

页数：5

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