Effect of pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of pravastatin)

被引：71
作者：
Masumoto, A [1 ]
Hirooka, Y [1 ]
Hironaga, K [1 ]
Eshima, K [1 ]
Setoguchi, S [1 ]
Egashira, K [1 ]
Takeshita, A [1 ]
机构：
[1] Kyushu Univ, Grad Sch Med Sci, Dept Cardiovasc Med, Higashi Ku, Fukuoka 8128582, Japan
来源：
AMERICAN JOURNAL OF CARDIOLOGY | 2001年 / 88卷 / 11期
基金：
日本学术振兴会;
关键词：
D O I：
10.1016/S0002-9149(01)02090-2
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We examined the effect of pravastatin on endothelial function in patients with coronary artery disease but without hypercholesterolemia. Our results suggest that short-term treatment with pravastatin improves impaired endothelial function in patients by mediating the increase in nitric oxide production.
引用
收藏
页码：1291 / +
页数：5
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