Flecainide Suppresses Defibrillator-Induced Storming in Catecholaminergic Polymorphic Ventricular Tachycardia

被引：14
作者：
Hong, Robert A. [1 ]
Rivera, Kahealani K. [1 ]
Jittirat, Arksarapuk
Choi, Joon J. [1 ]
机构：
[1] John A Burns Sch Med, Queens Med Ctr, Dept Internal Med, Div Cardiol, Honolulu, HI 96813 USA
来源：
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY | 2012年 / 35卷 / 07期
关键词：
catecholaminergic polymorphic ventricular tachycardia; calsequestrin-2; ryanodine receptor; defibrillator-induced storming; mutation; flecainide; ARRHYTHMIAS; MUTATIONS; GENE;
D O I：
10.1111/j.1540-8159.2012.03421.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited condition associated with ventricular tachycardia (VT) triggered by exercise or sympathetic stress. Incessant VT may develop due to defibrillator-induced storminga condition where implantable cardioverter-defibrillator discharges result in a hyperadrenergic state, provoking further VT and defibrillator discharge. We describe the case of a 14-year-old boy with CPVT caused by a calsequestrin-2 mutation, who presented with defibrillator-induced storming refractory to beta-blockers, calcium-channel blockers, amiodarone, and dronedarone. Flecainide and beta-blocker use suppressed incessant VT and defibrillator-induced storming. (PACE 2012;XX:e1e4)
引用
收藏
页码：794 / 797
页数：4
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