The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository

被引:201
作者
Jernigan, Terry L. [1 ,2 ,3 ]
Brown, Timothy T. [4 ,5 ]
Hagler, Donald J., Jr. [4 ,6 ]
Akshoomoff, Natacha [1 ,3 ]
Bartsch, Hauke [4 ]
Newman, Erik [1 ,3 ]
Thompson, Wesley K. [3 ,7 ]
Bloss, Cinnamon S. [8 ]
Murray, Sarah S. [9 ]
Schork, Nicholas [10 ]
Kennedy, David N. [11 ]
Kuperman, Joshua M. [4 ,6 ]
McCabe, Connor [12 ]
Chung, Yoonho [13 ]
Libiger, Ondrej [8 ]
Maddox, Melanie [1 ]
Casey, B. J. [14 ]
Chang, Linda [15 ]
Ernst, Thomas M. [15 ]
Frazier, Jean A. [11 ]
Gruen, Jeffrey R. [16 ,17 ]
Sowell, Elizabeth R. [18 ]
Kenet, Tal [19 ]
Kaufmann, Walter E. [20 ]
Mostofsky, Stewart [21 ]
Amaral, David G. [22 ]
Dale, Anders M. [2 ,4 ,5 ,6 ]
机构
[1] Univ Calif San Diego, Ctr Human Dev, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Dept Cognit Sci, La Jolla, CA 92093 USA
[3] Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA
[4] Univ Calif San Diego, Multimodal Imaging Lab, La Jolla, CA 92093 USA
[5] Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
[6] Univ Calif San Diego, Dept Radiol, La Jolla, CA 92093 USA
[7] Univ Calif San Diego, Stein Inst Res Aging, La Jolla, CA 92093 USA
[8] Univ Calif San Diego, Qualcomm Inst, La Jolla, CA 92093 USA
[9] Univ Calif San Diego, Dept Pathol, La Jolla, CA 92093 USA
[10] J Craig Venter Inst, Human Biol, La Jolla, CA USA
[11] Univ Massachusetts, Sch Med, Dept Psychiat, Boston, MA 02125 USA
[12] Univ Washington, Dept Psychol, Seattle, WA 98195 USA
[13] Yale Univ, Dept Psychol, New Haven, CT 06520 USA
[14] Weill Cornell Med Coll, Sackler Inst Dev Psychobiol, New York, NY USA
[15] Univ Hawaii, Dept Med, Queens Med Ctr, Honolulu, HI 96822 USA
[16] Yale Univ, Sch Med, Dept Pediat, New Haven, CT 06510 USA
[17] Yale Univ, Sch Med, Dept Genet, New Haven, CT 06510 USA
[18] Univ So Calif, Dept Pediat, Childrens Hosp Los Angeles, Los Angeles, CA 90089 USA
[19] Massachusetts Gen Hosp, Athinoula A Martinos Ctr Biomed Imaging, Dept Neurol, Charlestown, MA USA
[20] Boston Childrens Hosp, Boston, MA USA
[21] Johns Hopkins Univ, Sch Med, Kennedy Krieger Inst, Baltimore, MD USA
[22] Univ Calif Davis, Dept Psychiat & Behav Sci, Davis, CA 95616 USA
关键词
PROSPECTIVE MOTION CORRECTION; SURFACE-BASED ANALYSIS; HUMAN CEREBRAL-CORTEX; GEOMETRICALLY ACCURATE; ALZHEIMERS-DISEASE; MRI; SEGMENTATION; THICKNESS; ADMIXTURE; UTILITY;
D O I
10.1016/j.neuroimage.2015.04.057
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The main objective of the multi-site Pediatric Imaging, Neurocognition, and Genetics (PING) study was to create a large repository of standardized measurements of behavioral and imaging phenotypes accompanied by whole genome genotyping acquired from typically-developing children varying widely in age (3 to 20 years). This cross-sectional study produced sharable data from 1493 children, and these data have been described in several publications focusing on brain and cognitive development. Researchers may gain access to these data by applying for an account on the PING portal and filing a data use agreement. Here we describe the recruiting and screening of the children and give a brief overview of the assessments performed, the imaging methods applied, the genetic data produced, and the numbers of cases for whom different data types are available. We also cite sources of more detailed information about the methods and data. Finally we describe the procedures for accessing the data and for using the PING data exploration portal. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码:1149 / 1154
页数:6
相关论文
共 45 条
[21]   Whole brain segmentation: Automated labeling of neuroanatomical structures in the human brain [J].
Fischl, B ;
Salat, DH ;
Busa, E ;
Albert, M ;
Dieterich, M ;
Haselgrove, C ;
van der Kouwe, A ;
Killiany, R ;
Kennedy, D ;
Klaveness, S ;
Montillo, A ;
Makris, N ;
Rosen, B ;
Dale, AM .
NEURON, 2002, 33 (03) :341-355
[22]   Measuring the thickness of the human cerebral cortex from magnetic resonance images [J].
Fischl, B ;
Dale, AM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (20) :11050-11055
[23]   Thresholding of statistical maps in functional neuroimaging using the false discovery rate [J].
Genovese, CR ;
Lazar, NA ;
Nichols, T .
NEUROIMAGE, 2002, 15 (04) :870-878
[24]   Admixture and Clinical Phenotypic Variation [J].
Goetz, Laura H. ;
Uribe-Bruce, Liliana ;
Quarless, Danjuma ;
Libiger, Ondrej ;
Schork, Nicholas J. .
HUMAN HEREDITY, 2014, 77 (1-4) :73-86
[25]   Smoothing and cluster thresholding for cortical surface-based group analysis of fMRI data [J].
Hagler, Donald J., Jr. ;
Saygin, Ayse Pinar ;
Sereno, Martin I. .
NEUROIMAGE, 2006, 33 (04) :1093-1103
[26]   Automated White-Matter Tractography Using a Probabilistic Diffusion Tensor Atlas: Application to Temporal Lobe Epilepsy [J].
Hagler, Donald J., Jr. ;
Ahmadi, Mazyar E. ;
Kuperman, Joshua ;
Holland, Dominic ;
McDonald, Carrie R. ;
Halgren, Eric ;
Dale, Anders M. .
HUMAN BRAIN MAPPING, 2009, 30 (05) :1535-1547
[27]   Nonlinear registration of longitudinal images and measurement of change in regions of interest [J].
Holland, Dominic ;
Dale, Anders M. .
MEDICAL IMAGE ANALYSIS, 2011, 15 (04) :489-497
[28]   Efficient correction of inhomogeneous static magnetic field-induced distortion in Echo Planar Imaging [J].
Holland, Dominic ;
Kuperman, Joshua M. ;
Dale, Anders M. .
NEUROIMAGE, 2010, 50 (01) :175-183
[29]   The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods [J].
Jack, Clifford R., Jr. ;
Bernstein, Matt A. ;
Fox, Nick C. ;
Thompson, Paul ;
Alexander, Gene ;
Harvey, Danielle ;
Borowski, Bret ;
Britson, Paula J. ;
Whitwell, Jennifer L. ;
Ward, Chadwick ;
Dale, Anders M. ;
Felmlee, Joel P. ;
Gunter, Jeffrey L. ;
Hill, Derek L. G. ;
Killiany, Ron ;
Schuff, Norbert ;
Fox-Bosetti, Sabrina ;
Lin, Chen ;
Studholme, Colin ;
DeCarli, Charles S. ;
Krueger, Gunnar ;
Ward, Heidi A. ;
Metzger, Gregory J. ;
Scott, Katherine T. ;
Mallozzi, Richard ;
Blezek, Daniel ;
Levy, Joshua ;
Debbins, Josef P. ;
Fleisher, Adam S. ;
Albert, Marilyn ;
Green, Robert ;
Bartzokis, George ;
Glover, Gary ;
Mugler, John ;
Weiner, Michael W. .
JOURNAL OF MAGNETIC RESONANCE IMAGING, 2008, 27 (04) :685-691
[30]   Reliability in multi-site structural MRI studies: Effects of gradient non-linearity correction on phantom and human data [J].
Jovicich, J ;
Czanner, S ;
Greve, D ;
Haley, E ;
van der Kouwe, A ;
Gollub, R ;
Kennedy, D ;
Schmitt, F ;
Brown, G ;
MacFall, J ;
Fischl, B ;
Dale, A .
NEUROIMAGE, 2006, 30 (02) :436-443