Ultrasmall iron oxide nanoparticles: Synthesis, physicochemical, and magnetic properties

被引：7
|
作者：
Bae, Sung-Jin [2 ,3 ]
Park, Ji-Ae [3 ]
Lee, Jae-Jun [3 ]
Lee, Gang-Ho [4 ]
Kim, Tae-Jeong [5 ]
Yoo, Done-Sik [6 ]
Chang, Yongmin [1 ]
机构：
[1] Kyungpook Natl Univ, Dept Diagnost Radiol & Mol Med, Taegu 702701, South Korea
[2] Keimyung Univ, Dongsan Med Ctr, Dept Radiol, Daegu 700712, South Korea
[3] Kyungpook Natl Univ, Dept Med & Biol Engn, Taegu 702701, South Korea
[4] Kyungpook Natl Univ, Dept Chem, Taegu 702701, South Korea
[5] Kyungpook Natl Univ, Dept Appl Chem, Taegu 702701, South Korea
[6] ETRI, IT BT Grp, Taejon 305700, South Korea
来源：
CURRENT APPLIED PHYSICS | 2009年 / 9卷
关键词：
MRI; T2 contrast agent; USPIO; PCLNP; RING-OPENING POLYMERIZATION;
D O I：
10.1016/j.cap.2008.08.039
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
A new synthetic method leading to the formation of polycaprolactone (PCL)/iron oxide nanoparticles using polyvinylpyrrolidone (PVP) is described. The unique feature of this method is that the conventional polymerization step can be avoided. A stable colloidal dispersion of the PCL-coated iron oxide nanoparticles (PCLNP) is thus formed in the presence of PVP as a stabilizer. The PCLNP has a mean diameter of 20-50 nm as measured by TEM. Magnetic measurement by SQUID shows that the PCLNP has a strong superparamagnetism to be used as a liver MR T2 agent. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码：S19 / S21
页数：3
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