Fragmentation of 120 and 200 MeV u-1 4He ions in water and PMMA targets

被引：30

作者：

Rovituso, M. ^{[1
]}

Schuy, C. ^{[1
]}

Weber, U. ^{[1
]}

Brons, S. ^{[2
]}

Cortes-Giraldo, M. A. ^{[3
]}

La Tessa, C. ^{[4
]}

Piasetzky, E. ^{[5
]}

Izraeli, D. ^{[5
]}

Schardt, D. ^{[1
]}

Toppi, M. ^{[6
]}

Scifoni, E. ^{[1
,7
]}

Kraemer, M. ^{[1
]}

Durante, M. ^{[1
,7
]}

机构：

[1] GSI Helmholtzzentrum Schwerionenforsch, Darmstadt, Germany

[2] Heidelberger Ionenstrahl Therapiezentrum, Heidelberg, Germany

[3] Univ Seville, Seville, Spain

[4] NASA, Space Radiat Lab, Brookhaven Natl Lab, Upton, NY USA

[5] Tel Aviv Univ, IL-69978 Tel Aviv, Israel

[6] Ist Nazl Fis Nucl, Lab Nazl Frascati, Frascati, Italy

[7] INFN Trento, TIFPA, Povo, TN, Italy

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 2017年 / 62卷 / 04期

关键词：

particle therapy; helium ions; nuclear fragmentation; REACTION CROSS-SECTIONS; PARTICLE THERAPY; ALPHA-PARTICLES; HELIUM-IONS; HIGH-ENERGY; C-12; CHARGE; RADIOTHERAPY; CHALLENGES; HYDROGEN;

D O I：

10.1088/1361-6560/aa5302

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Recently, the use of He-4 particles in cancer radiotherapy has been reconsidered as they potentially represent a good compromise between protons and C-12 ions. The first step to achieve this goal is the development of a dedicated treatment planning system, for which basic physics information such as the characterization of the beam lateral scattering and fragmentation cross sections are required. In the present work, the attenuation of 4He primary particles and the build-up of secondary charged fragments at various depths in water and polymethyl methacrylate were investigated experimentally for 120 and 200 MeV u(-1) beams delivered by the synchrotron at the Heidelberg Ion-Beam Therapy Center, Heidelberg. Species and isotope identification was accomplished combining energy loss and time-of-flight measurements. Differential yields and energy spectra of all fragments types were recorded between 0 degrees and 20 degrees with respect to the primary beam direction.

引用

页码：1310 / 1326

页数：17

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