Preparation of desymmetrised meso-tartrate derivatives -: synthesis and utility of (R′,R′,R,S)-2,3-butane diacetal protected dimethyl tartrate

被引：33

作者：

Dixon, DJ ^{[1
]}

Foster, AC ^{[1
]}

Ley, SV ^{[1
]}

Reynolds, DJ ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 12期

关键词：

D O I：

10.1039/a902733e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of 2,3-butane diacetal protected dimethyl tartrate (R',R',R,S)-1 using a chiral memory protocol and its utility for the preparation of desymmetrised meso-tartrate derivatives through selective transesterification and aminolysis of the spatially different carboxylate termini is described.

引用

页码：1631 / 1633

页数：3

共 28 条

[21] Asymmetric desymmetrization of sigma-symmetrical diols: The role of chelation in the diastereoselective acetal cleavage induced by the chiral alpha-sulfinyl carbanion [J].