One-Pot Synthesis of Allylic Sulfones, Ketosulfones, and Triflyl Allylic Alcohols from Domino Reactions of Allylic Alcohols with Sulfinic Acid under Metal-Free Conditions

被引：61

作者：

Chu, Xue-Qiang ^{[1
,2
]}

Meng, Hua ^{[1
,2
]}

Xu, Xiao-Ping ^{[1
,2
]}

Ji, Shun-Jun ^{[1
,2
]}

机构：

[1] Soochow Univ, Coll Chem Chem Engn & Mat Sci, Key Lab Organ Synth Jiangsu Prov, Suzhou 215123, Peoples R China

[2] Soochow Univ, Collaborat Innovat Ctr Suzhou Nano Sci & Technol, Suzhou 215123, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2015年 / 21卷 / 32期

基金：

中国国家自然科学基金;

关键词：

iodine; metal-free reactions; multicomponent reactions; sulfur; sulfonylation; EFFICIENT SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; OXIDATIVE REARRANGEMENTS; AEROBIC DIFUNCTIONALIZATION; SELECTIVE OXIDATION; HYDROGEN-PEROXIDE; ALPHA-ARYLATION; RING EXPANSION; BOND FORMATION; C-S;

D O I：

10.1002/chem.201500469

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A metal-free tandem procedure by using a sulfonylation reaction of aryl allylic alcohols followed by an iodobenzenediacetate (PIDA)-promoted oxidative functionalization has been established. Allylic sulfones, -ketosulfones, and triflyl allylic alcohols have been constructed in a single operation. The methodology incorporates the sulfonyl (both aryl and triflyl) functionality with a simple work-up procedure.

引用

页码：11359 / 11368

页数：10

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