Early life predictors of atrial fibrillation-related mortality: Evidence from the health and retirement study

被引:7
作者
Glymour, M. Maria [1 ]
Benjamin, Emelia J. [2 ,3 ,4 ,5 ]
Kosheleva, Anna [1 ]
Gilsanz, Paola [1 ]
Curtis, Lesley H. [6 ]
Patton, Kristen K. [7 ]
机构
[1] Harvard Univ, Sch Publ Hlth, Dept Soc Human Dev & Hlth, Boston, MA 02115 USA
[2] Boston Univ, Sch Med, Sch Publ Hlth, Cardiol Sect,Dept Med,Dept Epidemiol, Boston, MA 02118 USA
[3] Boston Univ, Sch Med, Sch Publ Hlth, Prevent Med Sect,Dept Med,Dept Epidemiol, Boston, MA 02118 USA
[4] Boston Univ, Framingham, MA USA
[5] NHLBI, Framingham Heart Study, Framingham, MA USA
[6] Duke Univ, Sch Med, Duke Clin Res Inst, Durham, NC USA
[7] Univ Washington, Dept Med, Div Cardiol, Seattle, WA USA
关键词
Atrial fibrillation; Mortality; Residence; Geographic; Lifecourse; LIFECOURSE SOCIAL CONDITIONS; CORONARY-HEART-DISEASE; LOW-BIRTH-WEIGHT; UNITED-STATES; STROKE BELT; CARDIOVASCULAR-DISEASE; RISK-FACTOR; 1ST STROKE; CHILDHOOD; HEIGHT;
D O I
10.1016/j.healthplace.2012.12.008
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Prior research found that Americans born in 6 southeastern states (the AF-risk zone) had elevated risk of AF-related mortality, but no mechanisms were identified. We hypothesized the association between AF-related mortality and AF-risk zone birth is explained by indicators of childhood social disadvantage or adult risk factors. In 24,323 participants in the US Health and Retirement Study, we found that birth in the AF-risk zone was significantly associated with hazard of AF-related mortality. Among whites, the relationship was specific to place of birth, rather than place of adult residence. Neither paternal education nor subjectively assessed childhood SES predicted AF-related mortality. Conventional childhood and adult cardiovascular risk factors did not explain the association between place of birth and AF-related mortality. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:133 / 139
页数:7
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