Recent experiences with hexadimethrine for neutralizing heparin after cardiopulmonary bypass

被引：10

作者：

Cooney, A ^{[1
]}

Mann, TJ ^{[1
]}

机构：

[1] Royal Perth Hosp, Dept Anaesthesia, Perth, WA, Australia

来源：

ANAESTHESIA AND INTENSIVE CARE | 1999年 / 27卷 / 03期

关键词：

blood; anticoagulants : hexadimethrine bromide; protamine; adverse cardiovascular reactions; heparin neutralization;

D O I：

10.1177/0310057X9902700314

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Hexadimethrine bromide was used for the neutralization of heparin during cardiac surgery in the late 1950s. For some years, this institution has used it for patients who may be allergic to protamine. In view of the recent renewal of interest in hexadimethrine, we present four cases outlining its use during cardiac procedures in such patients. Other. drugs for reversing the action of heparin such as heparinase or platelet factor IV are not yet widely available.

引用

页码：298 / 300

页数：3

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