Sequential Release of Single-stranded DNAs from Gold Nanorods Triggered by Near-infrared Light Irradiation

被引：6

作者：

Fukushima, Hiromitsu ^{[1
]}

Yamashita, Shuji ^{[1
]}

Mori, Takeshi ^{[1
]}

Katayama, Yoshiki ^{[1
,2
,3
]}

Niidome, Takuro ^{[1
,2
,3
]}

机构：

[1] Kyushu Univ, Dept Appl Chem, Nishi Ku, Fukuoka 8190395, Japan

[2] Kyushu Univ, Ctr Future Chem, Nishi Ku, Fukuoka 8190395, Japan

[3] Kyushu Univ, Int Res Ctr Mol Syst, Nishi Ku, Fukuoka 8190395, Japan

来源：

CHEMISTRY LETTERS | 2012年 / 41卷 / 07期

基金：

日本学术振兴会; 日本科学技术振兴机构;

关键词：

ENERGY-TRANSFER; GENE DELIVERY; NANOPARTICLES; DRUG; THERAPY;

D O I：

10.1246/cl.2012.711

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Gold nanorods were modified with two types of double-stranded DNAs (dsDNA) with different melting temperatures. Irradiated by near-infrared laser light, the modified gold nanorods were heated, and single-stranded DNAs were released faster from the dsDNA with the lower melting temperature. Such combinations of different kinds of dsDNA allow us to construct a two-step release system of different types of oligonucleotides.

引用

页码：711 / 712

页数：2

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