Multiple myeloma presenting as bilateral breast lumps in pregnant woman

被引：9

作者：

Bouzguenda, Racem ^{[1
]}

Khanfir, Afef ^{[1
]}

Toumi, Nabil ^{[1
]}

Chaaben, Kais ^{[2
]}

Hentati, Yosr ^{[3
]}

Ayadi, Lobna ^{[4
]}

Feki, Wiem ^{[3
]}

Daoud, Jamel ^{[5
]}

Frikha, Mounir ^{[1
]}

机构：

[1] Habib Bourguiba Univ Hosp, Dept Med Oncol, Sfax 3029, Tunisia

[2] Hedi Chaker Univ Hosp, Dept Gynecol & Obstet, Sfax 3029, Tunisia

[3] Hedi Chaker Univ Hosp, Dept Radiol, Sfax 3029, Tunisia

[4] Habib Bourguiba Univ Hosp, Dept Pathol, Sfax 3029, Tunisia

[5] Habib Bourguiba Univ Hosp, Dept Radiotherapy, Sfax 3029, Tunisia

来源：

INTERNATIONAL JOURNAL OF HEMATOLOGY | 2013年 / 98卷 / 04期

关键词：

Multiple myeloma; Pregnancy; Treatment; Breast lumps; MANAGEMENT;

D O I：

10.1007/s12185-013-1420-y

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Multiple myeloma (MM) is a systemic disease in the elderly. Its incidence in patients younger than 40 years old and especially in pregnant women is extremely rare. MM may involve extraosseous sites, and only in rare cases it is observed in the breast. We describe the case of a 39-year-old woman diagnosed with an IgG lambda light-chain MM (Durie-Salmon stage IIIA, International Staging System II) in the 26th week of pregnancy, presenting with bilateral breast lumps. Dexamethasone (20 mg/m(2)/day on days 1-4, 9-12, and 17-20) was given as an induction agent to decrease tumor mass during pregnancy. Adverse response to dexamethasone was minor with excellent tolerance. A healthy baby was delivered at week 34 of gestation. Breast nodules revealing MM are extremely rare. Clinical and radiological features are atypical. Presentation during pregnancy is extremely rare, making anti-MM treatment potentially challenging.

引用

页码：487 / 490

页数：4

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