Quality of life after management of advanced osteoradionecrosis of the mandible

被引：41

作者：

Jacobson, A. S. ^{[1
]}

Zevallos, J. ^{[1
]}

Smith, M. ^{[2
]}

Lazarus, C. L. ^{[1
]}

Husaini, H. ^{[1
]}

Okay, D. ^{[1
]}

Buchbinder, D. ^{[1
]}

Persky, M. ^{[1
]}

Urken, M. L. ^{[1
]}

机构：

[1] Albert Einstein Coll Med, Dept Otolaryngol Head & Neck Surg, Beth Israel Med Ctr, New York, NY 10003 USA

[2] Albert Einstein Coll Med, Dept Surg, Beth Israel Med Ctr, Div Plast Surg, New York, NY 10003 USA

来源：

INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 2013年 / 42卷 / 09期

关键词：

osteoradionecrosis; quality of life; radiation therapy; functional outcomes; mandible reconstruction; NECK-CANCER PATIENTS; RADIATION-THERAPY; ORAL-CANCER; HEAD; RECONSTRUCTION; RADIOTHERAPY; PERFORMANCE; CARCINOMA; VALIDITY; SPEECH;

D O I：

10.1016/j.ijom.2013.03.022

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Osteoradionecrosis (ORN) of the mandible is a severe complication of radiation therapy for head and neck cancer. In this case series, the authors analyzed their treatment and quality of life outcomes over the past 6 years. A retrospective chart review of 42 patients treated surgically for advanced ORN was conducted. A telephone survey was conducted and quality of life (QOL) questionnaires were completed in a subset of patients. 30 patients responded to the telephone survey assessing QOL for speech, swallowing and overall functioning correlated with oral nutrition and performance status. Surgery for ORN can result in an improved QOL. Functional outcomes of oral intake, speech intelligibility, and eating in public correlated with patient rated QOL measures. A lack of improvement in QOL, despite the restoration of an intact mandible, relates to the, persistent effects of chemoradiotherapy.

引用

页码：1121 / 1128

页数：8

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