Cryptococcosis mimicking lung carcinoma with brain metastases in an immunocompetent patient

被引:3
作者
Ang, Samantha Y. L. [1 ]
Ng, Victor W. L. [2 ]
Kumar, Shree Dinesh [3 ]
Low, Sharon Y. Y. [1 ]
机构
[1] Natl Neurosci Inst, Dept Neurosurg, Singapore, Singapore
[2] Changi Gen Hosp, Dept Lab Med, Singapore, Singapore
[3] Changi Gen Hosp, Dept Orthopaed, Singapore, Singapore
关键词
Brain metastasis; Cryptococcus neoformans; Disseminated cryptococcosis; MAGNETIC-RESONANCE-SPECTROSCOPY; DIAGNOSIS; ABSCESSES;
D O I
10.1016/j.jocn.2016.09.016
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Cryptococcosis is a fungal infection caused by Cryptococcus spp. that enters the body via inhalation. This ubiquitous yeast has gained notoriety as an opportunistic pathogen in the immunosuppressed population. The authors report a case of a previously-well adult male presented with left-sided weakness. Imaging demonstrated a pulmonary mass and 2 contrast-enhancing intracranial lesions all features suggestive of a primary lung carcinoma with brain metastases. However, further investigations confirmed disseminated cryptococcosis, without evidence of malignancy. The patient was successfully treated with a course of antifungals. To the authors' knowledge, this is the first reported case of dissemintated cryptococcosis in an immunocompetent adult male, simulating as primary lung carcinoma with brain metastases. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:73 / 75
页数:3
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