SYNOVIAL SARCOMA OF THE HEAD AND NECK: RARE CASE OF CERVICAL METASTASIS

被引：15

作者：

Ishiki, Hiroto ^{[1
]}

Miyajima, Chie ^{[2
]}

Nakao, Kazunari ^{[3
]}

Asakage, Takahiro ^{[3
]}

Sugasawa, Masashi ^{[4
]}

Motoi, Toru ^{[5
]}

机构：

[1] Shizuoka Canc Ctr, Div Head & Neck Surg, Shizuoka, Japan

[2] Metropolitan Bokutoh Hosp, Dept Otorhinolaryngol, Tokyo, Japan

[3] Univ Tokyo, Dept Otorhinolaryngol Head & Neck Surg, Tokyo, Japan

[4] Saitama Med Sch Hosp, Dept Otorhinolaryngol Head & Neck Surg, Saitama, Japan

[5] Mem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10021 USA

来源：

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2009年 / 31卷 / 01期

关键词：

synovial sarcoma; head and neck; cervical metastasis; SYT-SSX; neck dissection; TRANSLOCATION X-18; SYT-SSX; IDENTIFICATION; EXPERIENCE; PLEURA; TUMORS;

D O I：

10.1002/hed.20856

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Background. Synovial sarcoma is a rarely encountered soft tissue sarcoma. Surgery with a wide surgical margin is the treatment of choice. However, there is no consensus on the treatment of head and neck synovial sarcoma in patients with cervical metastasis. Methods, A 20-year-old man was seen with a palpable mass in the right neck. He had been diagnosed with synovial sarcoma of the right tonsil and treated by surgery 1 and a half years before; therefore, the mass detected was thought to be a cervical metastasis of synovial sarcoma. We performed a modified radical neck dissection with no postoperative treatment. The pathological diagnosis was confirmed by detecting the SS-specific fusion gene SYT-SSX1. Results. The patient remains free of recurrence or metastasis 2 years and 10 months after the surgery. Conclusions. We encountered a case of head and neck synovial sarcoma with cervical metastasis that was successfully treated. (C) 2008 Wiley Periodicals, Inc. Head Neck 31: 131135,2009

引用

页码：131 / 135

页数：5

共 36 条

[1] Monophasic synovial sarcoma of the neck in an 8-year-old girl resembling a thyroglossal duct cyst
Alberty, J
Dockhorn-Dworniczak, B
[J]. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2002, 63 (01) : 61 - 65
[2] HEAD AND NECK SYNOVIAL CELL-SARCOMA
AMBLE, FR
OLSEN, KD
NASCIMENTO, AG
FOOTE, RL
[J]. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 1992, 107 (05) : 631 - 637
[3] Primary renal synovial sarcoma - Molecular and morphologic delineation of an entity previously included among embryonal sarcomas of the kidney
Argani, P
Faria, PA
Epstein, JI
Reuter, VE
Perlman, EJ
Beckwith, JB
Ladanyi, M
[J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2000, 24 (08) : 1087 - 1096
[4] Primary monophasic synovial sarcoma of the pleura - Five cases confirmed by the presence of SYT-SSX fusion transcript
Aubry, MC
Bridge, JA
Wickert, R
Tazelaar, HD
[J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2001, 25 (06) : 776 - 781
[5] Bergh P, 1999, CANCER-AM CANCER SOC, V85, P2596, DOI 10.1002/(SICI)1097-0142(19990615)85:12<2596::AID-CNCR16>3.0.CO
[6] 2-K
[7] SYNOVIAL SARCOMAS OF THE HEAD AND NECK
CARRILLO, R
RODRIGUEZPERALTO, JL
BATSAKIS, JG
[J]. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 1992, 101 (04) : 367 - 370
[8] CHOONG PFM, 1995, INT J ONCOL, V7, P161
[9] Cihak RA, 1997, HEAD NECK-J SCI SPEC, V19, P549
[10] IDENTIFICATION OF NOVEL GENES, SYT AND SSX, INVOLVED IN THE T(X18)(P11.2Q11.2) TRANSLOCATION FOUND IN HUMAN SYNOVIAL SARCOMA
CLARK, J
ROCQUES, PJ
CREW, AJ
GILL, S
SHIPLEY, J
CHAN, AML
GUSTERSON, BA
COOPER, CS
[J]. NATURE GENETICS, 1994, 7 (04) : 502 - 508

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