Ultrasound Retinal Stimulation: A Mini-Review of Recent Developments

被引：9
|
作者：
Lu, Gengxi [1 ,2 ]
Qian, Xuejun [1 ,2 ]
Gong, Chen [1 ]
Ji, Jie [1 ]
Thomas, Biju B. [2 ]
Humayun, Mark S. [1 ,2 ,3 ]
Zhou, Qifa [1 ,2 ,3 ]
机构：
[1] Univ Southern Calif, Dept Biomed Engn, Los Angeles, CA 90089 USA
[2] Univ Southern Calif, Roski Eye Inst, Keck Sch Med, Los Angeles, CA 90033 USA
[3] Univ Southern Calif, USC Ginsburg Inst Biomed Therapeut, Los Angeles, CA 90033 USA
来源：
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL | 2022年 / 69卷 / 12期
基金：
美国国家卫生研究院;
关键词：
High-frequency ultrasound; retina degeneration; retina prosthesis; ultrasound stimulation; visual prosthesis; PROSTHESIS; SYSTEM;
D O I：
10.1109/TUFFC.2022.3220568
中图分类号：
O42 [声学];
学科分类号：
070206 ; 082403 ;
摘要：
Ultrasound neuromodulation is an emerging technology. A significant amount of effort has been devoted to investigating the feasibility of noninvasive ultrasound retinal stimulation. Recent studies have shown that ultrasound can activate neurons in healthy and degenerated retinas. Specifically, high-frequency ultrasound can evoke localized neuron responses and generate patterns in visual circuits. In this review, we recapitulate pilot studies on ultrasound retinal stimulation, compare it with other neuromodulation technologies, and discuss its advantages and limitations. An overview of the opportunities and challenges to develop a noninvasive retinal prosthesis using high-frequency ultrasound is also provided.
引用
收藏
页码：3224 / 3231
页数：8
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