Investigation of Chemical Compounds, Antioxidant and Antimicrobial Properties of Teucrium arduini L. (Lamiaceae)

被引：24

作者：

Kremer, Dario ^{[1
]}

Kosir, Iztok Joze ^{[2
]}

Kosalec, Ivan ^{[1
]}

Koncic, Marijana Zovko ^{[1
]}

Potocnik, Tanja ^{[2
]}

Cerenak, Andreja ^{[2
]}

Bezic, Nada ^{[3
]}

Srecec, Sinisa ^{[4
]}

Dunkic, Valerija ^{[3
]}

机构：

[1] Univ Zagreb, Fac Pharm & Biochem, HR-10000 Zagreb, Croatia

[2] Slovenian Inst Hop Res & Brewing, SI-3310 Zhalec, Slovenia

[3] Univ Split, Fac Sci & Math, HR-210000 Split, Croatia

[4] Krizevci Coll Agr, HR-48260 Krizhevci, Croatia

来源：

CURRENT DRUG TARGETS | 2013年 / 14卷 / 09期

关键词：

Antimicrobial activity; antioxidant capacity; essential oils; phenolic compounds; Teucrium arduini; ESSENTIAL OIL; ANTIPHYTOVIRAL ACTIVITY; FLAVONOIDS; EXTRACTS; FRUITS;

D O I：

10.2174/1389450111314090009

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In this paper chemical composition of the essential oil (analysed by GC and GC-MS), the content of phenolic compounds (analysed by HPLC), quantity of total phenols and total flavonoids (analysed by UV/Vis spectrophotometer), antioxidant and antimicrobial activities of ethanolic extracts were investigated in endemic Teucrium arduini L. in population of Mt Biokovo (Croatia). The oil was characterized by a high concentration of sesquiterpene hydrocarbons (70.4%) of which beta-caryophyllene (35.2%) and germacrene D (18.7%) being the major compounds. Three phenolic compounds (quercetin, ferulic acid and rosmarinic acid) were identified and quantified in ethanolic extract of T. arduini using HPLC. The results also showed that T. arduini is a source of polyphenolic and other antioxidants with radical-scavenging and chelating properties. The ethanol extracts prepared from the leaf of T. arduini showed broad spectrum of antimicrobial activity on Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans and Aspergillus brasiliensis, which are susceptible on concentration below or equal to 4.00 mg/mL, whilst Microsporum gypseum was resistant at investigated concentrations.

引用

页码：1006 / 1014

页数：9

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