High-Intensity Interval Training is Associated with Improved Long-Term Survival in Heart Failure Patients

被引:20
作者
Hsu, Chih-Chin [1 ,2 ,3 ]
Fu, Tieh-Cheng [1 ,3 ,4 ]
Yuan, Shin-Sheng [5 ]
Wang, Chao-Hung [4 ,6 ]
Liu, Min-Hui [4 ,7 ]
Shyu, Yu-Chiau [3 ,8 ,9 ]
Cherng, Wen-Jin [10 ]
Wang, Jong-Shyan [11 ]
机构
[1] Keelung Chang Gung Mem Hosp, Dept Phys Med & Rehabil, Keelung 204, Taiwan
[2] Chang Gung Univ, Coll Med, Sch Tradit Chinese Med, Taoyuan 333, Taiwan
[3] Keelung Chang Gung Mem Hosp, Community Med Res Ctr, Keelung 204, Taiwan
[4] Keelung Chang Gung Mem Hosp, Heart Failure Res Ctr, Dept Internal Med, Cardiol Sect, Keelung 204, Taiwan
[5] Acad Sinica, Inst Stat Sci, Taipei 115, Taiwan
[6] Keelung Chang Gung Mem Hosp, Dept Internal Med, Div Cardiol, Keelung 204, Taiwan
[7] Ching Kuo Inst Management & Hlth, Dept Nursing, Keelung 203, Taiwan
[8] Acad Sinica, Inst Mol Biol, Taipei 115, Taiwan
[9] Chang Gung Univ Sci & Technol, Dept Nursing, Taoyuan 333, Taiwan
[10] Linkou Chang Gung Mem Hosp, Dept Internal Med, Div Cardiol, Taoyuan 333, Taiwan
[11] Chang Gung Univ, Coll Med, Inst Rehabil Sci, Dept Physiotherapy, Taoyuan 333, Taiwan
关键词
heart failure; cardiac rehabilitation; ventricular remodeling; oxygen consumption; cumulative survival rate; PRESERVED EJECTION FRACTION; FUNCTIONAL-CAPACITY; EXERCISE CAPACITY; ECONOMIC BURDEN; EPIDEMIOLOGY; HEMODYNAMICS; METAANALYSIS; DYSFUNCTION; GUIDELINES; HEALTH;
D O I
10.3390/jcm8030409
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This matched-control cohort study explored the effects of high-intensity interval training (HIIT) on left ventricle (LV) dimensions and survival in heart failure (HF) patients between 2009 and 2016. HF patients who underwent the multidisciplinary disease management program (MDP) were enrolled. Non-exercising participants, aged (mean (95% confidence interval)) 62.8 (60.1-65.5) years, were categorized as the MDP group (n = 101). Participants aged 61.5 (58.7-64.2) years who had completed 36 sessions of HIIT were treated as the HIIT group (n = 101). Peak oxygen consumption (VO2peak) and LV geometry were assessed during the 8-year follow-up period. The 5-year all-cause mortality risk factors and overall survival rates were determined in the longitudinal observation. An increased VO2peak of 14-20% was observed in the HIIT group after exercise training. Each 1-mL/kg/min increase in VO2peak conferred a 58% improvement in 5-year mortality. Increased LV end-systolic diameter (LVESD) was significantly (p = 0.0198) associated with increased mortality. The 8-month survival rate was significantly improved (p = 0.044) in HIIT participants compared to non-exercise participants. HF patients with VO2peak >= 14.0 mL/kg/min and LVESD <44 mm had a significantly better 5-year survival rate (98.2%) than those (57.3%) with lower VO2peak and greater LVESD. Both HIIT-induced increased VO2peak and decreased LVESD are associated with improved survival in HF patients.
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页数:14
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