Corneal ulceration and perforation with ketorolac tromethamine (Acular®) use after PRK

被引：39
作者：
Mian, SI
Gupta, A
Pineda, R
机构：
[1] Univ Michigan, WK Kellogg Eye Ctr, Cornea & External DisCataract & Refract Surg Serv, Ann Arbor, MI 48105 USA
[2] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Boston, MA 02115 USA
来源：
CORNEA | 2006年 / 25卷 / 02期
关键词：
corneal perforation; NSAID; ketorolac tromethamine; Acular (R); PRK;
D O I：
10.1097/01.ico.0000179931.05275.dd
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose: To report a case of corneal ulceration and perforation after PRK connected with high doses of ketorolac tromethamine (Acular (R)). Methods: A 31-year-old man presented 5 days after PRK in the left eye with corneal ulceration and perforation requiring penetrating keratoplasty. The patient admitted to using Acular (R) every hour, ciprofloxocin every hour, and prednisolone acetate 1% QID postoperatively. Results: Laboratory tests, including corneal cultures, were normal A diagnosis of corneal ulceration secondary to incorrect use of high dose ketorolac tromethamine was made. Conclusion: Judicious patient counseling is recommended when using topical NSAIDs in the setting of PRK.
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页码：232 / 234
页数：3
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