How strong is the association between abdominal obesity and the incidence of type 2 diabetes?

被引:151
作者
Freemantle, N. [1 ]
Holmes, J. [2 ]
Hockey, A. [3 ]
Kumar, S. [4 ]
机构
[1] Univ Birmingham, Hlth Care Evaluat Grp, Sch Primary Care Occupat & Publ Hlth, Birmingham B15 2TT, W Midlands, England
[2] PMSI Healthcare, London, England
[3] Sanofi Aventis, Guildford, Surrey, England
[4] Univ Warwick, Clin Sci Res Inst, Warwick, England
关键词
D O I
10.1111/j.1742-1241.2008.01805.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Quantitative evidence on the strength of the association between abdominal obesity and the incidence of type 2 diabetes was assessed. Methods: Systematic review of longitudinal studies assessing the relationship between measures reflecting abdominal obesity and the incidence of type 2 diabetes. Results: There was a strong association between measures reflecting abdominal obesity and the incidence of type 2 diabetes, the pooled odds ratio was 2.14 (95% CI: 1.70-2.71; p < 0.0001). Waist circumference (WC) was at least as good as other measures in predicting outcome. Conclusions: There is a strong association between measures reflecting abdominal obesity and the development of type 2 diabetes. Reducing WC may reduce the risk of developing type 2 diabetes.
引用
收藏
页码:1391 / 1396
页数:6
相关论文
共 18 条
[1]   Visceral adiposity and risk of type 2 diabetes - A prospective study among Japanese Americans [J].
Boyko, EJ ;
Fujimoto, WY ;
Leonetti, DL ;
Newell-Morris, L .
DIABETES CARE, 2000, 23 (04) :465-471
[2]  
Carey VJ, 1997, AM J EPIDEMIOL, V145, P614, DOI 10.1093/oxfordjournals.aje.a009158
[3]   OBESITY AND BODY-FAT DISTRIBUTION IN RELATION TO THE INCIDENCE OF NON-INSULIN-DEPENDENT DIABETES-MELLITUS - A PROSPECTIVE COHORT STUDY OF MEN IN THE NORMATIVE AGING STUDY [J].
CASSANO, PA ;
ROSNER, B ;
VOKONAS, PS ;
WEISS, ST .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1992, 136 (12) :1474-1486
[4]  
Chihaoui M, 2001, DIABETES METAB, V27, P487
[5]   Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies [J].
de Koning, Lawrence ;
Merchant, Anwar T. ;
Pogue, Janice ;
Anand, Sonia S. .
EUROPEAN HEART JOURNAL, 2007, 28 (07) :850-856
[6]  
Gavin JR, 1997, DIABETES CARE, V20, P1183
[7]   INCREASED INCIDENCE OF DIABETES-MELLITUS IN RELATION TO ABDOMINAL ADIPOSITY IN OLDER WOMEN [J].
KAYE, SA ;
FOLSOM, AR ;
SPRAFKA, JM ;
PRINEAS, RJ ;
WALLACE, RB .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 1991, 44 (03) :329-334
[8]   REGIONAL ADIPOSITY AND MORBIDITY [J].
KISSEBAH, AH ;
KRAKOWER, GR .
PHYSIOLOGICAL REVIEWS, 1994, 74 (04) :761-811
[9]  
Knowler WC, 2002, NEW ENGL J MED, V346, P393, DOI 10.1056/NEJMoa012512
[10]  
McNeely MJ, 2001, AM J CLIN NUTR, V74, P101