Clec12a: Quieting the Dead

被引：4

作者：

Yamasaki, Sho ^{[1
]}

机构：

[1] Kyushu Univ, Div Mol Immunol, Res Ctr Infect Dis, Med Inst Bioregulat,Higashi Ku, Fukuoka 8128582, Japan

来源：

IMMUNITY | 2014年 / 40卷 / 03期

关键词：

MICL CLEC12A; IMMUNITY; IDENTIFICATION; ACTIVATION; CRYSTALS; RECEPTOR; CELLS;

D O I：

10.1016/j.immuni.2014.03.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Immune activation as a result of the recognition of damage-associated molecular patterns needs to be controlled. In this issue of Immunity, Neumann et al. (2014) demonstrates that Clec12a is a receptor for dead cells through the recognition of uric acid crystals and contributes to the dampening of the responses.

引用

收藏

页码：309 / 311

页数：4

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