Metastatic Pulmonary Calcinosis and Leukocytoclastic Vasculitis in a Patient with Multiple Myeloma

被引：5

作者：

Cagirgani, Seckin ^{[1
]}

Soyer, Nur ^{[1
]}

Vural, Filiz ^{[1
]}

Saydam, Guray ^{[1
]}

Simsir, Ilgin Yildirim ^{[1
]}

Donmez, Ayhan ^{[1
]}

Akalin, Taner ^{[2
]}

Biceroglu, Selen ^{[3
]}

Tombuloglu, Murat ^{[1
]}

机构：

[1] Ege Univ, Sch Med, Dept Hematol, Izmir, Turkey

[2] Ege Univ, Sch Med, Dept Pathol, Izmir, Turkey

[3] Ege Univ, Sch Med, Dept Radiol, Izmir, Turkey

来源：

TURKISH JOURNAL OF HEMATOLOGY | 2012年 / 29卷 / 04期

关键词：

Multiple myeloma; Metastatic calcification; Leukocytoclastic vasculitis; CALCIFICATION; MANIFESTATIONS;

D O I：

10.5505/tjh.2012.23600

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Both leukocytoclastic vasculitis and metastatic pulmonary calcification are conditions that rarely occur during the course of multiple myeloma. We present a multiple myeloma patient that had severe dyspnea due to metastatic pulmonary calcinosis, and ulceronecrotic skin lesions caused by leukocytoclastic vasculitis. After 3 courses of standard-dose chemotherapy all skin and pulmonary lesions disappeared. Autologous peripheral stem cell transplantation was performed and during 1 year of follow-up the patient was in complete remission; after 1 year, laboratory test results indicated disease relapse. Although the patient was treated with bortezomib and dexamethasone, the disease progressed. Non-myeloablative allogeneic stem cell transplantation was performed, but despite of all treatment the patient died due to disease progression.

引用

页码：397 / 400

页数：4

共 17 条

[1] Metastatic calcinosis cutis in multiple myeloma [J].