Is the recent increment in attributable deaths to type-2 diabetes (T2D) associated with the latest chikungunya outbreak in a major epidemic area in Brazil?

被引：11

作者：

de Goes Cavalcanti, Luciano Pamplona ^{[1
]}

D'angelo, Sara Mendes ^{[1
]}

Queiroz Lemos, Daniele Rocha ^{[2
]}

de Almeida Barreto, Francisca Kalline ^{[1
]}

Siqueira, Andre Machado ^{[3
]}

Miyajima, Fabio ^{[4
,5
]}

机构：

[1] Univ Fed Ceara, Programa Posgrad Saude Publ, Fortaleza, Ce, Brazil

[2] Ctr Univ Christus, Fortaleza, CE, Brazil

[3] Fundacao Oswaldo Cruz, Inst Nacl Infectol Evandro Chagas, Rio De Janeiro, RJ, Brazil

[4] Univ Fed Ceara, Ctr Pesquisas Desenvolvimento Medicamentos, Fortaleza, CE, Brazil

[5] Univ Liverpool, Inst Translat Med, Liverpool, Merseyside, England

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2018年 / 51卷 / 01期

关键词：

Chikungunya; Diabetes; Arbovirus; Deaths; INFECTIOUS REPORTER VIRUS; YELLOW-FEVER-VIRUS; PARTICLES; EFFICIENT; 17DD;

D O I：

10.1590/0037-8682-0440-2017

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Introduction: Chikungunya virus (CHIKV) can negatively influence outcomes in patients with pre-existing conditions. We investigated the association between the recent CHIKV outbreak and increased type 2 diabetes (T2D)-attributable deaths. Methods: Monthly averages of T2D-attributable deaths between 2001 and 2016 were determined and compared to the equivalent data for 2017 and the recent CHIKV outbreak. Results: CHKV outbreak peaked in April 2017 with 4,394.4 cases/100,000 inhabitants, while T2D-attributable deaths in the same period increased by 35.2%. Conclusions: T2D-attributable deaths significantly increased compared to the previous data, which overlapped with CHIKV incidence. The pathophysiology of this association warrants further investigations.

引用

页码：63 / 70

页数：8

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