Immunohistochemical localization of phosphorylated AKT in multiple myeloma

被引：29

作者：

Alkan, S ^{[1
]}

Izban, KF ^{[1
]}

机构：

[1] Loyola Univ, Med Ctr, Dept Pathol, Maywood, IL 60153 USA

来源：

BLOOD | 2002年 / 99卷 / 06期

关键词：

D O I：

10.1182/blood-2001-01-0317

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2278 / 2279

页数：2

共 9 条

[1] The dynamics of protein kinase B regulation during B cell antigen receptor engagement [J].

Astoul, E ;

Watton, S ;

Cantrell, D .

JOURNAL OF CELL BIOLOGY, 1999, 145 (07) :1511-1520

[2] Translocation of Akt/PKB to the nucleus of osteoblast-like MC3T3-E1 cells exposed to proliferative growth factors [J].

Borgatti, P ;

Martelli, AM ;

Bellacosa, A ;

Casto, R ;

Massari, L ;

Capitani, S ;

Neri, LM .

FEBS LETTERS, 2000, 477 (1-2) :27-32

[3] Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor [J].

Brunet, A ;

Bonni, A ;

Zigmond, MJ ;

Lin, MZ ;

Juo, P ;

Hu, LS ;

Anderson, MJ ;

Arden, KC ;

Blenis, J ;

Greenberg, ME .

CELL, 1999, 96 (06) :857-868

[4] Cellular survival: a play in three Akts [J].

Datta, SR ;

Brunet, A ;

Greenberg, ME .

GENES & DEVELOPMENT, 1999, 13 (22) :2905-2927

[5] The AKT kinase is activated in multiple myeloma tumor cells [J].

Hsu, JH ;

Shi, YJ ;

Krajewski, S ;

Renner, S ;

Fisher, M ;

Reed, JC ;

Franke, TF ;

Lichtenstein, A .

BLOOD, 2001, 98 (09) :2853-2855

[6] Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas [J].

Kurose, K ;

Zhou, XP ;

Araki, T ;

Cannistra, SA ;

Maher, ER ;

Eng, C .

AMERICAN JOURNAL OF PATHOLOGY, 2001, 158 (06) :2097-2106

[7] Analysis of expression of nuclear factor κB (NF-κB) in multiple myeloma:: downregulation of NF-κB induces apoptosis [J].

Ni, H ;

Ergin, M ;

Huang, Q ;

Qin, JZ ;

Amin, HM ;

Martinez, RL ;

Saeed, S ;

Barton, K ;

Alkan, S .

BRITISH JOURNAL OF HAEMATOLOGY, 2001, 115 (02) :279-286

[8] Regulation of nuclear translocation of Forkhead transcription factor AFX by protein kinase B [J].

Takaishi, H ;

Konishi, H ;

Matsuzaki, H ;

Ono, Y ;

Shirai, Y ;

Saito, N ;

Kitamura, T ;

Ogawa, W ;

Kasuga, M ;

Kikkawa, U ;

Nishizuka, Y .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (21) :11836-11841

[9]

Tu YP, 2000, CANCER RES, V60, P6763

← 1 →